Compare Androderm vs. Testopel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Androderm
(Testosterone Patch)

Testopel
(Testosterone Implant)

Treats low testosterone. The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.Treats low testosterone. The testosterone implant is a good option for long-term testosterone therapy, but it can be expensive, and it's really important that you get the right dose so your doctor doesn't have to remove pellets.
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Reviews & ratings
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Side effects
AndrodermTestopel

The Androderm FDA package insert doesn’t have numbers about how common side effects are.

More about Androderm side effects »

The Testopel FDA package insert doesn’t have numbers about how common side effects are.

More about Testopel side effects »
How it works
AndrodermTestopel
The testosterone patch works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone implant works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
AndrodermTestopel
Hormone replacement
Testosterone
Prescription only
Hormone replacement
Testosterone
Prescription only
Available as
AndrodermTestopel
  • Patch
  • Implant pellet
Used for (click to learn more)
AndrodermTestopel
  • Low testosterone
  • Low testosterone
Risk factors for serious side effects
AndrodermTestopel
Coming soon.Coming soon.
Pregnancy category
AndrodermTestopel
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
  • Can cause increased acne and changes in sex drive.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
AndrodermTestopel
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
  • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
  • The testosterone patch only has to be placed once each night.
  • Your doctor will give this shot to you every 3 months, so you don't have to worry about administering it yourself like some testosterone injections.
  • Unlike topical forms of testosterone, you don't have to worry about accidentally transferring this medication to another person's skin.
Downsides and risks
AndrodermTestopel
  • Not available in generic.
  • You have to be careful to rotate the testosterone patch to a different part of your body each night.
  • Can cause skin irritation.
  • Has to be removed before you have an MRI.
  • The patch can become loose if you do heavy exercise or sweat a lot.
  • Not available in generic form, so it can be more expensive.
  • Your doctor has to calculate your dose for 3 months. If it ends up being too much, the doctor might have to remove some of the implant pellets.
  • The pellets can come out, although this is extremely rare.
Tips from our pharmacists for people taking the medication
AndrodermTestopel
  • Place the testosterone patch on a clean, dry area of your skin each night. Don't put it on your scrotum or a bony part of your body.
  • Change the area where you place the testosterone patch every night, and wait at least 7 days before you put in on the same site again.
  • Make sure the patch is attached to your skin, especially along the edges. If it loosens, smooth the edges and then the center of the patch with your finger to make sure it's attached completely.
  • If the patch falls off before noon, apply another patch. If it falls off after that, don't apply another patch until your regular time at night. Don't use tape to keep the patch attached.
  • Don't bathe or swim for at least 3 hours after you put a new patch on. Also, heavy exercise or lots of sweating can make your patch fall off.
  • Your doctor will give this you as a shot underneath your skin every 3 months.
  • Can cause nausea, vomiting and headache.
  • Can cause increased acne and changes in sex drive.
Learn more
More about AndrodermSide effectsReviews & ratingsAlternativesFDA package insert
More about TestopelSide effectsReviews & ratingsAlternativesFDA package insert