Compare Antara vs. Niaspan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Antara
(Fenofibrate)

Niaspan
(Niacin)

Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. niacin is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.3035714285714284Antara
Reviews for Antara (Fenofibrate)
27%
of people say Antara (Fenofibrate) is worth it
14%
say it works well
29%
say it's a big hassle
Reviews for Niaspan (Niacin)
43%
+16% vs. Antara (Fenofibrate)
31%
+17% vs. Antara (Fenofibrate)
19%
+10% vs. Antara (Fenofibrate)
Side effects
AntaraNiaspan
  • Abnormal liver function tests 7%
  • Increased ast 2%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
  • Constipation 1%
  • Increased alt 1%
More Antara side effects »
  • Flushing 50%
  • Itching 6%
  • Vomiting 5%
  • Nausea 4%
  • Cough increased 2%
  • Diarrhea 1%
More Niaspan side effects »
How it works
AntaraNiaspan
Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).niacin is a cholesterol-lowering medicine. Researchers don't know exactly how it works, but it seems to lower the amount of "bad" cholesterol (LDL) made by the liver. It may also help your body process cholesterol.
Type of medication
AntaraNiaspan
Cholesterol-lowering
Fibric acid
Prescription only
Cholesterol-lowering
Nicotinic acid
Prescription only
Available as
AntaraNiaspan
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
AntaraNiaspan
Risk factors for serious side effects
AntaraNiaspan
  • Taking Antara (Fenofibrate) with statins
  • Past history of liver disease
    • Taking Antara (Fenofibrate) with anticoagulants
            Detailed Antara (Fenofibrate) risks & warnings »
            • Taking Niaspan (Niacin) with statins
            • Heavy alcohol use
            • Past history of liver disease
            • Diabetes
            • Taking Niaspan (Niacin) with anticoagulants
            Detailed Niaspan (Niacin) risks & warnings »
            Pregnancy category
            AntaraNiaspan
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            CFDA pregnancy category (Weigh risks vs. benefits)

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            See the FDA package insert
            Alcohol
            • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
            • Don't drink a lot of alcohol while taking this medicine.
            • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
            • People who take Niaspan (Niacin) have reported liver damage, especially if taken with statins or if you drink large amounts of alcohol. This has been rare. Talk to your doctor if you've ever had liver disease as they may discuss alternatives, or they may monitor your liver with blood tests.
            Food
            No specific food-related info.
            • You have to take it before bedtime with a low-fat snack.
            • Take it at bedtime with a low-fat snack.
            • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
            Kidneys and liver
            • People on Antara (Fenofibrate) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
            • People on Niaspan (Niacin) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
            Sex
            No specific sex-related info.No specific sex-related info.
            Sleep
            No specific sleep-related info.No specific sleep-related info.
            Weight
            No specific weight-related info.No specific weight-related info.
            Upsides and benefits
            AntaraNiaspan
            • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
            • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
            • Lowers the risk of a second heart attack.
            • Good for lowering triglycerides (fats).
            Downsides and risks
            AntaraNiaspan
            • In studies, it didn't lower heart disease in people with Type 2 diabetes.
            • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
            • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
            • Different forms and strengths of this medication can't be substituted for each other.
            • By itself, niacin is not as effective as statins for improving cholesterol.
            • Can cause flushing and stomach pain or discomfort.
            • You have to take it before bedtime with a low-fat snack.
            • If you don't take it regularly, you might have to re-start the medicine at a lower dose.
            Tips from our pharmacists for people taking the medication
            AntaraNiaspan
            • Lowers triglycerides.
            • Can cause backache or headache.
            • Call your doctor if you develop muscle or abdominal pain.
            • Don't drink a lot of alcohol while taking this medicine.
            • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
            • You should use this medicine in combination with a healthy diet.
            • Take it at bedtime with a low-fat snack.
            • Avoid alcohol, spicy foods, and hot beverages right before you take this medicine.
            • Can cause flushing.
            • Call your doctor if you develop muscle pain.
            • Don't stop taking this medicine suddenly.
            Learn more
            More about AntaraSide effectsReviews & ratingsAlternativesFDA package insert
            More about NiaspanSide effectsReviews & ratingsAlternativesFDA package insert