Compare Antara vs. simvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Antara (fenofibrate)

Prescription only

Zocor (simvastatin)

Prescription only
Lowers cholesterol and triglycerides.

Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.

3.3/ 7 average rating with 56 reviewsforAntara
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

5.1/ 7 average rating with 1176 reviewsforsimvastatin
  • Antara (fenofibrate) can reduce triglycerides by about 20-50%.
  • Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
  • There is a less expensive generic version available.
  • You only need to take it once a day, with or without food.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
  • Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
  • Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
  • Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
  • Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
Used for
Dosage forms
  • Pill
  • Pill
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Side effects
10possible side effects
  • Abnormal liver function tests
  • Respiratory disorder
  • Stomach pain
  • Back pain
  • Headache
  • Increased AST
  • Increased ALT
  • Increased creatine phosphokinase
  • Nausea
  • Constipation
See more detailed side effects
The Zocor (simvastatin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Muscle pain

    Taking Antara (fenofibrate) with statins

    ...and 3 more risk factors

  • Liver damage

    History of liver disease

  • Gallstones

    History of gallstones

  • Increased bleeding risk

    Taking Antara (fenofibrate) with anticoagulants

See more detailed risks and warnings
  • Muscle pain and kidney damage

    Kidney disease

    ...and 4 more risk factors

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Harm to unborn baby


    ...and 1 more risk factors

  • Drug interactions

    Certain drugs can increase the dose of Zocor (simvastatin) in the body

  • High blood sugar

    History of high blood sugar

See more detailed risks and warnings