Compare Antara vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Antara
(Fenofibrate)

Zetia
(Ezetimibe)

Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. Zetia can improve your cholesterol, but it doesn't reduce heart attacks or heart disease, and it's expensive compared to other cholesterol-lowering medicines.
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Reviews & ratings
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3.3035714285714284Antara
Reviews for Antara (Fenofibrate)
27%
of people say Antara (Fenofibrate) is worth it
14%
say it works well
29%
say it's a big hassle
Reviews for Zetia (Ezetimibe)
42%
+15% vs. Antara (Fenofibrate)
34%
+20% vs. Antara (Fenofibrate)
20%
+9% vs. Antara (Fenofibrate)
Side effects
AntaraZetia
  • Abnormal liver function tests 7%
  • Increased ast 2%
  • Increased creatine phosphokinase 2%
  • Abdominal pain 1%
  • Inflammation inside the nose 1%
  • Constipation 1%
  • Increased alt 1%
More Antara side effects »
  • Ear, nose, or throat infection 1%
  • Sinus inflammation 1%
  • Arthtralgia 1%
More Zetia side effects »
How it works
AntaraZetia
Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Zetia is a cholesterol-lowering medicine. It prevents cholesterol absorption in your intestines, lowers the amount of cholesterol stored in your liver, and helps your body process cholesterol.
Type of medication
AntaraZetia
Cholesterol-lowering
Fibric acid
Prescription only
Cholesterol-lowering
Cholesterol inhibitor
Prescription only
Available as
AntaraZetia
  • Pill
  • Pill
Used for (click to learn more)
AntaraZetia
Risk factors for serious side effects
AntaraZetia
  • Taking Antara (Fenofibrate) with statins
  • Past history of liver disease
    • Taking Antara (Fenofibrate) with anticoagulants
            Detailed Antara (Fenofibrate) risks & warnings »
              • Taking Zetia (Ezetimibe) with statins
              • Past history of liver disease
              • Taking Zetia (Ezetimibe) with statins
              Detailed Zetia (Ezetimibe) risks & warnings »
              Pregnancy category
              AntaraZetia
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              Alcohol
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Don't drink a lot of alcohol while taking this medicine.
              No specific alcohol-related info.
              Food
              No specific food-related info.No specific food-related info.
              Kidneys and liver
              • People on Antara (Fenofibrate) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
              • People on Zetia (Ezetimibe) while taking statins have reported muscle pain which may lead to muscle and kidney damage. This has been very rare. Talk to your doctor if you develop sudden muscle pain or weakness or fever and you don't know why.
              Sex
              No specific sex-related info.No specific sex-related info.
              Sleep
              No specific sleep-related info.No specific sleep-related info.
              Weight
              No specific weight-related info.No specific weight-related info.
              Upsides and benefits
              AntaraZetia
              • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
              • Can be used with other medicines to improve cholesterol.
              • Available in a combination pill with simvastatin.
              Downsides and risks
              AntaraZetia
              • In studies, it didn't lower heart disease in people with Type 2 diabetes.
              • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
              • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
              • Different forms and strengths of this medication can't be substituted for each other.
              • Doesn't lower triglycerides (fats).
              • Hasn't been shown to lower the risk of heart attacks or heart disease.
              • By itself, Zetia is not as effective as statins for improving cholesterol.
              • There's no generic available, so it can be expensive.
              Tips from our pharmacists for people taking the medication
              AntaraZetia
              • Lowers triglycerides.
              • Can cause backache or headache.
              • Call your doctor if you develop muscle or abdominal pain.
              • Don't drink a lot of alcohol while taking this medicine.
              • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
              • You should use this medicine in combination with a healthy diet.
              • Lowers bad cholesterol, and raises good cholesterol.
              • Tell your doctor if you develop bone or muscle pain.
              • Can be used with other medications to lower cholesterol.
              • May cause diarrhea or raise your chance of getting colds.
              Learn more
              More about AntaraSide effectsReviews & ratingsAlternativesFDA package insert
              More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert