Compare Antara vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Antara
(fenofibrate)

Zetia
(ezetimibe)

Lowers cholesterol. Antara (Fenofibrate) is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol.Lowers cholesterol. Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.
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Coupons for Antara
Best available price for 30 (130mg) capsules of antara
Coupons for Zetia
Best available price for 30 (10mg) tablets of zetia
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.3Antara
Reviews for Antara
27%
of people (All ages) say Antara is worth it
14%
say it works well
29%
say it's a big hassle
Have you used Antara (fenofibrate)?
Worth itNot sureNot worth it
Reviews for Zetia
42%
-15% worse vs. Antara
34%
-20% worse vs. Antara
21%
-8% worse vs. Antara
128 reviews
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it
Side effects
AntaraZetia
  • Abnormal liver function tests 7%
  • Abdominal pain 1%
  • Increased ast 2%
  • Increased alt 1%
  • Increased creatine phosphokinase 2%
  • Constipation 1%
More Antara side effects »
  • Common cold 1%
  • Sore throat 4%
  • Sinus infection 1%
  • Abnormal liver tests 3%
  • Joint pain 1%
  • Pain in arms and legs 1%
  • Muscle pain 3%
More Zetia side effects »
How it works
AntaraZetia
Antara (Fenofibrate) is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Zetia (ezetimibe) is a cholesterol-lowering medicine. It stops your body from absorbing cholesterol in food and helps process other forms of cholesterol.
Type of medication
AntaraZetia
Prescription onlyPrescription only
Available as
AntaraZetia
  • Pill
  • Pill
Used for
AntaraZetia
Risk factors for serious side effects
AntaraZetia
  • Taking Antara (Fenofibrate) with statins
  • Past history of liver disease
  • Taking Antara (Fenofibrate) with anticoagulants
Detailed Antara (fenofibrate) risks & warnings »
  • Taking Zetia (ezetimibe) with statins
  • Past history of liver disease
Detailed Zetia (ezetimibe) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
AntaraZetia
  • Don't drink a lot of alcohol while taking this medicine.
  • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
No alcohol related info.
Kidneys and liver
AntaraZetia
  • Reports of liver damage have been reported in people who take Antara (Fenofibrate), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
  • Zetia (ezetimibe) can hurt your liver, especially if it is used with statins. Talk to your doctor if you have liver disease.
Upsides and benefits
AntaraZetia
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
Downsides and risks
AntaraZetia
  • In studies, it didn't lower heart disease in people with Type 2 diabetes.
  • According to new guidelines, you shouldn't take this medicine by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly can raise your risk of liver damage.
  • Different forms and strengths of this medication can't be substituted for each other.
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
Tips from our pharmacists for people taking the medication
AntaraZetia
  • Lowers triglycerides.
  • Can cause backache or headache.
  • Call your doctor if you develop muscle or abdominal pain.
  • Don't drink a lot of alcohol while taking this medicine.
  • Also taking Welchol or Questran? Take this medicine at least 1 hour before or 6 hours after.
  • You should use this medicine in combination with a healthy diet.
  • Lowers bad cholesterol and raises good cholesterol.
  • Tell your doctor if you develop bone or muscle pain.
  • Can be used with other medications to lower cholesterol.
  • Good alternative to statins if you can't tolerate statins or are unable to control cholesterol with statins alone.
  • Can cause diarrhea or increase your chance of getting colds.
Learn more
More about AntaraSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Antara (fenofibrate)?
Worth itNot sureNot worth it
More about ZetiaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zetia (ezetimibe)?
Worth itNot sureNot worth it