Compare Apidra vs. Glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Apidra
(Insulin Glulisine)

Diabeta
(Glyburide)

Coming soon.Lowers blood sugar. Glyburide is a very effective oral blood sugar-lowering medicine, but has more side effects and restrictions compared to other medicines in this class (sulfonylureas).
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Reviews & ratings
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Have you used Apidra (Insulin Glulisine)?
Worth itNot sureNot worth it
Reviews for Diabeta (Glyburide)
45%
-55% worse vs. Apidra (Insulin Glulisine)
34%
-66% worse vs. Apidra (Insulin Glulisine)
21%
-21% worse vs. Apidra (Insulin Glulisine)
110 reviews
Have you used Diabeta (Glyburide)?
Worth itNot sureNot worth it
Side effects
ApidraGlyburide

We haven’t found good data for Apidra side effects.

FDA side effect reports for Apidra »
  • Gastrointestinal disturbances 2%
  • Allergic skin reactions 2%
More Glyburide side effects »
How it works
ApidraGlyburide
Coming soon.Glyburide is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.
Type of medication
ApidraGlyburide
Prescription only
Available as
ApidraGlyburide
  • Injection
  • Pill
Used for
ApidraGlyburide
  • Diabetes Mellitus Type 1 Diabetes Mellitus Type 2
Risk factors for serious side effects
ApidraGlyburide
Coming soon.
    • Elderly
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
    • History of sulfa allergies
    Detailed Diabeta (Glyburide) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    ApidraGlyburide
    No alcohol related info.
    • Avoid drinking alcohol.
    Food
    ApidraGlyburide
    No food related info.
    • Eat regular, balanced meals to avoid low blood sugar.
    Kidneys and liver
    ApidraGlyburide
    No kidneys and liver related info.
    • Not a good choice for people with kidney problems because it's processed by the kidneys.
    Weight
    ApidraGlyburide
    No weight related info.
    • Can cause mild weight gain (2 to 3 pounds).
    • Can cause weight gain, dizziness, or stomach upset.
    Upsides and benefits
    ApidraGlyburide
    Coming soon
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • One of the least expensive diabetes medicines.
    Downsides and risks
    ApidraGlyburide
    Coming soon
    • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
    • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
    • Can cause mild weight gain (2 to 3 pounds).
    • Not preferred for people 65 years or older since it can cause prolonged low blood sugar (more than 12 hours).
    • Not a good choice for people with kidney problems because it's processed by the kidneys.
    • Loses effectiveness over time or as your body stops making insulin.
    Tips from our pharmacists for people taking the medication
    ApidraGlyburide
    Coming soon
    • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
    • Can cause weight gain, dizziness, or stomach upset.
    • Avoid drinking alcohol.
    • Eat regular, balanced meals to avoid low blood sugar.
    • Check your blood sugar regularly.
    Learn more
    More about ApidraSide effectsReviews & ratingsFDA package insert
    Have you used Apidra (Insulin Glulisine)?
    Worth itNot sureNot worth it
    More about GlyburideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Diabeta (Glyburide)?
    Worth itNot sureNot worth it