Compare Apidra vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Apidra (insulin glulisine)

Prescription only

Januvia (sitagliptin)

Prescription only
Controls blood sugar.

Apidra (insulin glulisine) is an insulin that controls blood sugar during your meals, but you'll still have to follow your doctor's diet and exercise plan.

Lowers your blood sugar.

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.

4.3/ 7 average rating with 143 reviewsforJanuvia
Upsides
  • Apidra (insulin glulisine) starts working in as soon as 15 minutes.
  • Programs are available to lower your copay. Talk to your doctor or pharmacist.
  • Can be used in people over 65 and children 4 years of age and older.
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
Downsides
  • Your doctor might have to check your kidneys and liver regularly if you've had kidney or liver problems in the past.
  • Since Apidra (insulin glulisine) is an injectable, it might not be a good treatment option for people who are afraid of needles.
  • Only available as a brand name, so Apidra (insulin glulisine) can be expensive.
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
Used for
Dosage forms
  • Injection
  • Pill
Price
Lowest price near you
$511.84
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Lowest price near you
$415.3
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Reviews
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143 
44%
think this treatment is worth it
34%
think this treatment works well
17%
think this treatment is a hassle

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Side effects
1possible side effects
  • Common cold
    11%
See more detailed side effects
3possible side effects
  • Common cold
    5%
  • Diarrhea
    3%
  • Abdominal pain
    2%
See more detailed side effects
Risks and warnings
  • Low blood sugar

    Changes in diet and exercise

    ...and 4 more risk factors

  • Low blood potassium levels

    Taking laxatives

    ...and 1 more risk factors

  • Fluid buildup

    Taking Avandia or Actos

See more detailed risks and warnings
  • Death from inflammation of the pancreas (pancreatitis)

    History of pancreatitis

    ...and 4 more risk factors

  • Kidney damage

    Pre-existing kidney damage

  • Low blood sugar (hypoglycemia)

    Taking medicines for diabetes

See more detailed risks and warnings