Compare Apidra vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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(Insulin Glulisine)


Coming soon.Lowers blood sugar. Januvia (Sitagliptin) is a good add-on treatment if your blood sugar is still too high, but you don't want to use an injectable medicine.
How it works
Coming soon.Januvia (Sitagliptin) is an anti-diabetic drug. It helps your body release more insulin in order to lower blood sugar.
Type of medication
Coming soon.
DPP-4 inhibitor
Prescription only
Available as
  • Injection
  • Pill
Used for (click to learn more)
  • Diabetes mellitus type 1 Diabetes mellitus type 2
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Reviews & ratings
Button Group. All currently active
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Reviews for Januvia (Sitagliptin)
57% vs. Apidra (Insulin Glulisine)
66% vs. Apidra (Insulin Glulisine)
17% vs. Apidra (Insulin Glulisine)
Side effects

We haven’t found good data for Apidra side effects.

FDA side effect reports for Apidra »
  • Common cold 2%
  • Diarrhea 1%
More Januvia side effects »
Risk factors for serious side effects
Coming soon.
      Detailed Januvia (Sitagliptin) risks & warnings »
      Pregnancy category
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      No specific alcohol-related info.No specific alcohol-related info.
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      No specific sleep-related info.No specific sleep-related info.
      No specific weight-related info.
      • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
      Upsides and benefits
      Coming soon.
      • Oral blood sugar-lowering medicine.
      • Lowers A1c levels by 0.5-0.8%. (Hemoglobin A1c measures your average blood sugar over time.)
      • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
      • Uses the hormones naturally produced by your body to affect how sugar is processed.
      • Unlike some diabetes medicines, it's unlikely to cause weight gain and low blood sugar.
      • You don't have to check your blood sugar every day with this medicine.
      Downsides and risks
      Coming soon.
      • Not as strong as other diabetes medicines. Your doctor might add it to your blood sugar-lowering regimen if your sugar levels are still too high.
      • Likely expensive since there's no generic version available.
      • Some people might get frequent throat infections or nasal congestion.
      Tips from our pharmacists for people taking the medication
      Coming soon.
      • Can cause headache and cold-like symptoms.
      • Tell your doctor about persistent stomach pain, nausea, vomiting, or loss of appetite.
      • Can be expensive depending on insurance coverage.
      • Check your blood sugar regularly.
      Learn more
      More about ApidraSide effectsReviews & ratingsFDA package insert
      More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert