Compare Apidra vs. metformin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Apidra
(insulin glulisine)

Glucophage
(metformin)

Coming soon.Lowers blood sugar. Glucophage (metformin) is the first choice medicine to control your blood sugar and lower the risk of death from diabetes, although a few people may not tolerate the stomach side effects.
Reviews & ratings
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Have you used Apidra (insulin glulisine)?
Worth itNot sureNot worth it
Reviews for metformin
65%
+35% better vs. Apidra
46%
+54% better vs. Apidra
16%
+16% better vs. Apidra
938 reviews
Have you used Glucophage (metformin)?
Worth itNot sureNot worth it
Side effects
Apidrametformin

We haven’t found good data for Apidra side effects.

FDA side effect reports for Apidra »
  • Diarrhea 41%
  • Nausea/vomiting 18%
  • Gas 6%
  • Weakness 3%
  • Indigestion 3%
  • Stomach pain 1%
  • Headache 1%
More metformin side effects »
How it works
Apidrametformin
Coming soon.Glucophage (metformin) is an anti-diabetic drug. It lowers the amount of sugar your body makes or absorbs, and allows your body use the existing insulin better.
Type of medication
Apidrametformin
Prescription only
Available as
Apidrametformin
  • Injection
  • Pill
  • Extended release pill
  • Liquid
Used for
Apidrametformin
  • Diabetes Mellitus Type 1 Diabetes Mellitus Type 2
Risk factors for serious side effects
Apidrametformin
    Coming soon.
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    Detailed Glucophage (metformin) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Alcohol
    Apidrametformin
    No alcohol related info.
    • Limit or avoid alcohol when taking this medicine.
    • Excessive or chronic alcohol use can increase the risk of a dangerous side effect.
    Food
    Apidrametformin
    No food related info.
    • Always take it with food to lessen stomach upset.
    Kidneys and liver
    Apidrametformin
    No kidneys and liver related info.
    • Glucophage (metformin) can cause this rare life-threatening condition. Your doctor will check your kidneys and liver before you start. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. You're more likely to get this if you already have kidney problems. Glucophage (metformin) should be stopped 48 hours before and after surgery or any imaging procedure needing contrast dye.
    • Usually not a good choice for people with kidney problems. Your doctor will tell you if Glucophage (metformin) is right for you to take.
    Weight
    Apidrametformin
    No weight related info.
    • Doesn't cause weight gain.
    Upsides and benefits
    Apidrametformin
    Coming soon
    • Improves sugar control and lowers A1c levels as much as 2%.
    • One of the few diabetes medicines that lowers the risk of death from diabetes-related complications.
    • Doesn't cause weight gain.
    • Rarely causes low blood sugar.
    Downsides and risks
    Apidrametformin
    Coming soon
    • Often causes stomach upset, like diarrhea, nausea, gas, or stomach cramping.
    • Usually not a good choice for people with kidney problems. Your doctor will tell you if Glucophage (metformin) is right for you to take.
    • Excessive or chronic alcohol use can increase the risk of a dangerous side effect.
    Tips from our pharmacists for people taking the medication
    Apidrametformin
    Coming soon
    • Can cause upset stomach with nausea and especially diarrhea in the first couple of weeks.
    • Always take it with food to lessen stomach upset.
    • Stay hydrated.
    • Limit or avoid alcohol when taking this medicine.
    • Tell your doctor about any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain.
    • Check your blood sugar regularly.
    Learn more
    More about ApidraSide effectsReviews & ratingsFDA package insert
    Have you used Apidra (insulin glulisine)?
    Worth itNot sureNot worth it
    More about metforminSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Glucophage (metformin)?
    Worth itNot sureNot worth it