Compare Apokyn vs. Azilect

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Apokyn (apomorphine)

Prescription only

Azilect (rasagiline)

Prescription only
Helps you move around.

Apokyn (apomorphine) is good for treating the "off" episodes or difficulty moving around when you have advanced Parkinson's disease, but it can cause vomiting and sudden sleepiness.

Treats Parkinson's disease.

Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.

Upsides
  • Preferred drug according to the guidelines to treat the "off" periods or inability to control movements well that's associated with Parkinson's.
  • People respond to the injection of Apokyn (apomorphine) very quickly and this response can last longer than other medicines.
  • Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
  • Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
  • Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
Downsides
  • Can cause vomiting and sudden sleepiness. Your doctor will have to give you a medicine to stop the vomiting from happening.
  • Apokyn (apomorphine) should only be used if you have an "off" period of moving around. You should keep using your other medicines for your Parkinson's.
  • Dosing can be confusing since the pen only dispenses in milliliters, and there have been reports of people getting overdoses of Apokyn (apomorphine) because they thought it was for milligrams.
  • Stopping Apokyn (apomorphine) suddenly or lowering the dose too quickly can cause your muscles to become very stiff and you might get a very high fever, which can be life threatening. Talk to your doctor if you want to stop taking this medicine.
  • It can cause unusual cravings and changes in behavior in some people.
Used for
Dosage forms
  • Injection
  • Pill
Price
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$1035.15
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Lowest price near you
$195.29
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Side effects
9possible side effects
  • Yawning
    40%
  • Movement problems
    35%
  • Drowsiness or sleepiness
    35%
  • Nausea or vomiting
    30%
  • Dizziness
    20%
  • Runny nose
    20%
  • Chest pain
    15%
  • Hallucinations
    10%
  • Swelling in arms and legs
    10%
See more detailed side effects
9possible side effects
  • Difficulty controlling movement
    18%
  • Headache
    14%
  • Accidental injury
    12%
  • Nausea
    12%
  • Falls
    11%
  • Weight loss
    9%
  • Constipation
    9%
  • Low blood pressure
    9%
  • Joint pain
    8%
See more detailed side effects
Risks and warnings
  • Hallucinations

    Taking antipsychotic medicines

  • Falling asleep during the day

    Taking other medicines for Parkinson's disease

  • Increased risk of heart attack or stroke

    History of heart disease or stroke

See more detailed risks and warnings
  • Increased blood pressure

    Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 7 more risk factors

  • Falling asleep during the day

    Taking other medicines for Parkinson's disease

  • Movement problems

    Taking other medicines for Parkinson's disease

  • Lack of impulse control

    Taking other medicines for Parkinson's disease

See more detailed risks and warnings