Compare Apokyn vs. Emsam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Apokyn
(apomorphine)

Eldepryl
(selegiline)

Helps you move around. Apokyn (apomorphine) is good for treating the "off" episodes or difficulty moving around when you have advanced Parkinson's disease, but it can cause vomiting and sudden sleepiness.Coming soon.
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Prices and coupon for 20 (3ml of 30mg/3ml) cartridges of apomorphine
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Prices and coupon for 60 (5mg) tablets of selegiline
Reviews & ratings
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Have you used Apokyn (apomorphine)?
Worth itNot sureNot worth it

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Have you used Eldepryl (selegiline)?
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Side effects
ApokynEmsam
  • Yawning 40%
  • Movement problems 24%
  • Drowsiness or sleepiness 35%
  • Nausea or vomiting 19%
  • Dizziness 20%
  • Runny nose 20%
  • Chest pain 15%
  • Hallucinations 10%
  • Swelling in arms and legs 10%
More Apokyn side effects »

We haven’t found good data for Emsam side effects.

FDA side effect reports for Emsam »
How it works
ApokynEmsam
Apokyn (apomorphine) is a non-ergoline dopamine agonist. Apokyn (apomorphine) allows you to move around more freely by stimulating the brain's ability to use dopamine, which is important for movement.Coming soon.
Type of medication
ApokynEmsam
Prescription only
Available as
ApokynEmsam
  • Injection
  • Pill
  • Patch
Used for
ApokynEmsam
  • Major Depressive Disorder
Risk factors for serious side effects
ApokynEmsam
    • Taking antipsychotic medicines
    • Taking other medicines for Parkinson's disease
    • History of heart disease or stroke
        Detailed Apokyn (apomorphine) risks & warnings »
        Coming soon.
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Sleep
        ApokynEmsam
        • Apokyn (apomorphine) can make you sleepy or fall asleep without warning. Don't drive or do anything that requires concentration until you know how it affects you.
        • Apokyn (apomorphine) can make you sleepy or fall asleep suddenly without warning. Don't drive or do anything that requires your full concentration until you know how Apokyn (apomorphine) affects you. You're more at risk if you're taking other medicines for Parkinson's. Talk to your doctor if this bothers you.
        No sleep related info.
        Upsides and benefits
        ApokynEmsam
        • Preferred drug according to the guidelines to treat the "off" periods or inability to control movements well that's associated with Parkinson's.
        • People respond to the injection of Apokyn (apomorphine) very quickly and this response can last longer than other medicines.
        Coming soon
        Downsides and risks
        ApokynEmsam
        • Can cause vomiting and sudden sleepiness. Your doctor will have to give you a medicine to stop the vomiting from happening.
        • Apokyn (apomorphine) should only be used if you have an "off" period of moving around. You should keep using your other medicines for your Parkinson's.
        • Dosing can be confusing since the pen only dispenses in milliliters, and there have been reports of people getting overdoses of Apokyn (apomorphine) because they thought it was for milligrams.
        • Stopping Apokyn (apomorphine) suddenly or lowering the dose too quickly can cause your muscles to become very stiff and you might get a very high fever, which can be life threatening. Talk to your doctor if you want to stop taking this medicine.
        Coming soon
        Tips from our pharmacists for people taking the medication
        ApokynEmsam
        • Apokyn (apomorphine) can cause nausea, so your doctor will give you medicine to help stop that and vomiting.
        • Your doctor will tell you how much Apokyn (apomorphine) you will inject. This is given in milliliters. Turn the pen so that the correct dose is given.
        • Apokyn (apomorphine) can make you sleepy or fall asleep without warning. Don't drive or do anything that requires concentration until you know how it affects you.
        • Always change where you inject Apokyn (apomorphine) and always use a fresh needle every time. This will make injecting safer and less painful.
        • If the liquid inside the Apokyn (apomorphine) cartridge does not look clear and colorless, don't use it. Use a new cartridge or call your pharmacy.
        • Can cause you to feel faint, especially if you get up after sitting or lying down for a while. Be careful moving around after you use Apokyn (apomorphine) so you don't fall.
        Coming soon
        Learn more
        More about ApokynSide effectsAlternativesFDA package insert
        Have you used Apokyn (apomorphine)?
        Worth itNot sureNot worth it
        More about EmsamSide effectsReviews & ratingsFDA package insert
        Have you used Eldepryl (selegiline)?
        Worth itNot sureNot worth it