Compare Arava vs. Rituxan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Arava
(Leflunomide)

Rituxan
(Rituximab)

Coming soon.Calms down your immune system. Rituxan (Rituximab) is effective for treating multiple types of cancer and arthritis. That said, you'll need to watch for possibly serious side effects, especially infusion reactions.
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Reviews & ratings
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Have you used Arava (Leflunomide)?
Worth itNot sureNot worth it

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Have you used Rituxan (Rituximab)?
Worth itNot sureNot worth it
Side effects
AravaRituxan

We haven’t found good data for Arava side effects.

FDA side effect reports for Arava »
  • Low blood phosphate 11%
  • Acute infusion reactions 8%
  • Cardiac side effect 1%
More Rituxan side effects »
How it works
AravaRituxan
Coming soon.Rituxan (Rituximab) is a monoclonal antibody. It targets a specific protein on white blood cells that makes it easier for your immune system to find and destroy cancerous cells. It also relieves symptoms and slows the progression of Rheumatoid Arthritis.
Type of medication
AravaRituxan
Coming soon.
Immunosuppressant
Immunomodulator
Antirheumatic
Biological response modifier
Anticancer
Biological response modifier
Prescription only
Available as
AravaRituxan
  • Pill
  • Infusion (IV)
Used for (click to learn more)
AravaRituxan
  • Rheumatoid arthritis
Risk factors for serious side effects
AravaRituxan
Coming soon.
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
    • Taking Rituxan (Rituximab) with immunosuppressant drugs (if using for RA)
    • Taking Rituxan (Rituximab) with chemotherapy (if using for NHL or CLL
    • Stem cell transplant
      • Taking Rituxan (Rituximab) for Non-Hodgkin's Lymphoma (NHL)
      • Rapidly growing tumors
      • History of heart problems
      • Drug interactions
      • Start of therapy with Rituxan (Rituximab)
        Detailed Rituxan (Rituximab) risks & warnings »
        Pregnancy

        Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Kidneys and liver
        AravaRituxan
        No kidneys and liver related info.
        • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
        Upsides and benefits
        AravaRituxan
        Coming soon
        • Treats leukemia, lymphoma, and blood vessel inflammation.
        • Also treats moderate to severe rheumatoid arthritis that hasn't responded to anti-TNF treatment (but you'll need to take methotrexate too).
        • The chance of having a reaction to the infusion is highest during your first dose, but the risk decreases each time you get Rituxan (Rituximab). It usually happens within 30 minutes to 2 hours after starting the infusion.
        • Rituxan (Rituximab) is a targeted therapy that works differently than chemotherapy. Both work well when they're taken together, especially when treating CLL and NHL.
        Downsides and risks
        AravaRituxan
        Coming soon
        • Only your doctor or other trained medical staff can administer Rituxan (Rituximab), so you'll need to go into an office or clinic for every dose.
        • Not the best choice if you have heart problems.
        • Rituxan (Rituximab) can stay in your body for up to 6 months after you complete treatment. Men and women who are able to have children need to use birth control for up to one year after finishing Rituxan (Rituximab).
        • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
        Tips from our pharmacists for people taking the medication
        AravaRituxan
        Coming soon
        • Rituxan (Rituximab) is given as an IV infusion by trained medical staff in a clinic or hospital.
        • You'll need to be monitored in the clinic in case you have a serious or life-threatening reaction during the infusion, but you can take other medications that'll lower your risk of this happening.
        • It's very important that you read the Medication Guide before you start taking Rituxan (Rituximab).
        • Rituxan (Rituximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, a cough that doesn't go away, or flu-like symptoms.
        • Use effective birth control while you're taking Rituxan (Rituximab) and for 12 months after you finish treatment.
        • Don't get live vaccines while you're taking Rituxan (Rituximab).
        Learn more
        More about AravaSide effectsReviews & ratingsFDA package insert
        Have you used Arava (Leflunomide)?
        Worth itNot sureNot worth it
        More about RituxanSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Rituxan (Rituximab)?
        Worth itNot sureNot worth it