Compare Arixtra vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Coming soon.Prevents blood clots. Coumadin (Warfarin) is an old, cheap, and effective medicine to prevent blood clots, but it requires some monitoring, dose adjustments, and even lifestyle changes.
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Reviews & ratings
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Reviews for Coumadin (Warfarin)
+61% vs. Arixtra (Fondaparinux)
+54% vs. Arixtra (Fondaparinux)
21% vs. Arixtra (Fondaparinux)
512 reviews
Side effects

We haven’t found good data for Arixtra side effects.

FDA side effect reports for Arixtra »

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »
How it works
Coming soon.Coumadin (Warfarin) is an anticoagulant blood thinner. It lowers chemicals called clotting factors so that it's harder for your body to form blood clots.
Type of medication
Coming soon.
Vitamin K antagonist
Prescription only
Available as
  • Injection
  • Pill
Used for (click to learn more)
  • Deep venous thrombosis
Risk factors for serious side effects
Coming soon.
  • Dose too high
  • Age greater than 65
  • History of gastrointestinal bleeding
  • High blood pressure
  • Kidney or liver problems
  • Drug interactions
  • Change in lifestyle or diet
  • Illnesses
  • Alcohol
  • Certain genetic makeup
    • Women of childbearing age
    Detailed Coumadin (Warfarin) risks & warnings »
    Pregnancy category
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    XFDA pregnancy category (Unsafe)

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    See the FDA package insert
    No specific alcohol-related info.
    • Many lifestyle factors can affect how well warfarin works, such as diet, alcohol, and activity level, so it's important that you try to stay consistent with your behaviors.
    No specific food-related info.
    • Eat foods containing consistent amounts of Vitamin K.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    No specific sex-related info.No specific sex-related info.
    No specific sleep-related info.No specific sleep-related info.
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    Coming soon.
    • Oral blood-thinning medicine that prevents blood clots from forming or getting bigger.
    • Prevents complications of blood clots that can cause extreme discomfort or death. Examples include stroke (blood clots in the brain), pulmonary embolism (blood clots in the lungs causing trouble breathing), or deep vein thrombosis (blood clots in the legs causing pain and blood vessel damage).
    • Has an antidote, Vitamin K, in case of a major accidental bleeding.
    • Coumadin (Warfarin) has been around for a long time, so we know a lot about how well it works and what the risks are.
    • It's dirt cheap.
    Downsides and risks
    Coming soon.
    • Raises your risk of bleeding and bruising.
    • Requires routine blood testing (called an INR) to see how well the medicine is working for you and to make the dose just right for you.
    • Many lifestyle factors can affect how well warfarin works, such as diet, alcohol, and activity level, so it's important that you try to stay consistent with your behaviors.
    • Lots of interactions with other drugs or supplements. Always check with your doctor or pharmacist before starting any new meds.
    Tips from our pharmacists for people taking the medication
    Coming soon.
    • Thins your blood to prevent clots from forming or getting bigger. Doesn't break up existing clots.
    • The amount you need depends on your diet, other medical problems, and genes.
    • Take it exactly as instructed.
    • Can raise your risk of bleeding or bruising.
    • Requires regular blood tests to get your dose right.
    • Interacts with a lot of medicines and supplements. Don't start any new meds without talking to your doctor.
    • Eat foods containing consistent amounts of Vitamin K.
    • Tell your doctor immediately if you fell or if you have unusual bleeding, bruising, swelling, or changes in vision and coordination.
    • Get a medical bracelet so that people know you're on a blood thinner during an emergency situation.
    Learn more
    More about ArixtraSide effectsFDA package insert
    More about CoumadinSide effectsReviews & ratingsAlternativesFDA package insert