Compare Arixtra vs. Eliquis

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Arixtra (fondaparinux)

Prescription only

Eliquis (apixaban)

Prescription only
Thins the blood and treats blood clots.

Arixtra (fondaparinux) is effective at treating clots, but it can increase your risk of bleeding.

Prevents blood clots.

Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.

5.3/ 7 average rating with 19 reviewsforEliquis
Upsides
  • Arixtra (fondaparinux) is effective at treating blood clots in the extremeties and those that have travelled to the lungs.
  • A generic form is available.
  • Arixtra (fondaparinux) is a safe option for use in patients who have experienced a rare, life-threatening reaction to another anticoagulant, heparin.
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
Downsides
  • Arixtra (fondaparinux) should be used with caution in patients with kidney problems, as this can lead to an accumulation of the medication and increase the risk of bleeding.
  • Arixtra (fondaparinux) can cause a drop in platelet count, which can increase your risk of bleeding.
  • People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when taking Arixtra (fondaparinux).
  • Periodic blood tests and monitoring of your kidneys is important.
  • You have to inject yourself everyday with this medication.
  • The anti blood-clotting effects of Arixtra (fondaparinux) may remain for up to 4 days after stopping this medication in normal patients, and there is no current antidote.
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
Used for
  • Treatment of blood clots
Dosage forms
  • Injection
  • Pill
Price
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$3005.75
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Lowest price near you
$405.63
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Reviews
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19 
47%
think this treatment is worth it
58%
think this treatment works well
21%
think this treatment is a hassle

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Side effects
2possible side effects
  • Anemia
    2%
  • Blood clots
    2%
See more detailed side effects
1possible side effects
  • Major bleed
    2%
See more detailed side effects
Risks and warnings
  • Spinal/epidural blood clots

    Indwelling epidural catheters

    ...and 3 more risk factors

  • Bleeding

    Existing condition that increases risk of bleeding

    ...and 5 more risk factors

  • Kidney problems

    Kidney problems

  • Allergic reactions

    Latex allergy

See more detailed risks and warnings
  • Increased risk of stroke or blood clots from early discontinuation

    Stopping Eliquis (apixaban) prematurely

  • Paralysis in the spine

    Spinal puncture (spinal tap)

    ...and 3 more risk factors

  • Increased risk of stroke or bleeding

    Artificial heart valve

  • Increased side effects in kidney or liver conditions

    Current kidney problems

    ...and 1 more risk factors

See more detailed risks and warnings