Compare Arixtra vs. Lovenox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Arixtra (fondaparinux)

Prescription only

Lovenox (Enoxaparin)

Prescription only
Thins the blood and treats blood clots.

Arixtra (fondaparinux) is effective at treating clots, but it can increase your risk of bleeding.

Prevents blood clots.

Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.

4.0/ 5 average rating with 19 reviewsforLovenox
Upsides
  • Arixtra (fondaparinux) is effective at treating blood clots in the extremeties and those that have travelled to the lungs.
  • A generic form is available.
  • Arixtra (fondaparinux) is a safe option for use in patients who have experienced a rare, life-threatening reaction to another anticoagulant, heparin.
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
Downsides
  • Arixtra (fondaparinux) should be used with caution in patients with kidney problems, as this can lead to an accumulation of the medication and increase the risk of bleeding.
  • Arixtra (fondaparinux) can cause a drop in platelet count, which can increase your risk of bleeding.
  • People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when taking Arixtra (fondaparinux).
  • Periodic blood tests and monitoring of your kidneys is important.
  • You have to inject yourself everyday with this medication.
  • The anti blood-clotting effects of Arixtra (fondaparinux) may remain for up to 4 days after stopping this medication in normal patients, and there is no current antidote.
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
Used for
Dosage forms
  • Injection
  • Injection
Price
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Reviews
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19 reviews so far
63%
saidit'sworth it
63%
saiditworked well
16%
saidit'sa big hassle

Have you used Lovenox (Enoxaparin)?

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Side effects
2possible side effects
  • Anemia
    2%
  • Blood clots
    2%
See more detailed side effects
7possible side effects
  • Fever
    5%
  • Major hemorrhage
    4%
  • Hemorrhage
    4%
  • Nausea
    3%
  • Peripheral edema
    3%
  • Anemia
    2%
  • Edema
    2%
See more detailed side effects
Risks and risk factors
  • Spinal/epidural blood clots
    • Indwelling epidural catheters
    • Use of other medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or other anticoagulants
    • History of traumatic or repeated epidural or spinal puncture
    • History of spinal surgery
  • Bleeding
    • Existing condition that increases risk of bleeding
    • Surgery
    • Use of other anticoagulants
    • Kidney problems
    • Patients with low body weight (<50kg)
    • Elderly (>75 years old)
  • Kidney problems
    • Kidney problems
  • Decreased platelet count
  • Allergic reactions
    • Latex allergy
See more detailed risks and warnings
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • Taking NSAIDs or other blood thinning medicines
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Older age
  • Increased risk of stroke or increased risk of blood clots
    • Stopping Lovenox (Enoxaparin) early
  • Clotting problems
    • Heparin-induced thrombocytopenia
See more detailed risks and warnings