Compare Arixtra vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Arixtra (fondaparinux)

Prescription only

Pradaxa (Dabigatran)

Prescription only
Thins the blood and treats blood clots.

Arixtra (fondaparinux) is effective at treating clots, but it can increase your risk of bleeding.

Prevents blood clots.

Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.

Upsides
  • Arixtra (fondaparinux) is effective at treating blood clots in the extremeties and those that have travelled to the lungs.
  • A generic form is available.
  • Arixtra (fondaparinux) is a safe option for use in patients who have experienced a rare, life-threatening reaction to another anticoagulant, heparin.
  • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
  • Doesn't require regular blood tests or frequent dose changes.
  • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
Downsides
  • Arixtra (fondaparinux) should be used with caution in patients with kidney problems, as this can lead to an accumulation of the medication and increase the risk of bleeding.
  • Arixtra (fondaparinux) can cause a drop in platelet count, which can increase your risk of bleeding.
  • People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when taking Arixtra (fondaparinux).
  • Periodic blood tests and monitoring of your kidneys is important.
  • You have to inject yourself everyday with this medication.
  • The anti blood-clotting effects of Arixtra (fondaparinux) may remain for up to 4 days after stopping this medication in normal patients, and there is no current antidote.
  • Not available as generic.
  • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
  • Can't take during pregnancy.
Used for
Dosage forms
  • Injection
  • Pill
Price
Lowest price
$3005.75
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
2possible side effects
  • Anemia
    2%
  • Blood clots
    2%
See more detailed side effects
10possible side effects
  • GI side effect
    35%
  • Any side effect
    21%
  • Any bleed
    20%
  • Dyspepsia
    8%
  • Major gastrointestinal bleed
    6%
  • Major bleed
    3%
  • GI bleed
    3%
  • Gastritis-like symptoms
    3%
  • Life-threatening bleed
    2%
  • Gastrointestinal bleed
    2%
See more detailed side effects
Risks and risk factors
  • Spinal/epidural blood clots
    • Indwelling epidural catheters
    • Use of other medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or other anticoagulants
    • History of traumatic or repeated epidural or spinal puncture
    • History of spinal surgery
  • Bleeding
    • Existing condition that increases risk of bleeding
    • Surgery
    • Use of other anticoagulants
    • Kidney problems
    • Patients with low body weight (<50kg)
    • Elderly (>75 years old)
  • Kidney problems
    • Kidney problems
  • Decreased platelet count
  • Allergic reactions
    • Latex allergy
See more detailed risks and warnings
  • Blood clots
    • Stopping Pradaxa (Dabigatran) too soon
  • Blood clot in the spine
    • Spinal tap
    • Anesthesia along the spine (epidural anesthesia)
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Unusual bleeding
    • Drug interactions
    • Taking with NSAIDs, aspirin, or other blood-thinning medicines
  • Stomach or intestinal problems
  • Increased risk of stroke or bleeding
    • Artificial heart valve
See more detailed risks and warnings