Treats inflammatory bowel disease. Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.
Calms down your immune system. Humira (Adalimumab) is very effective at calming down your immune system, but it's expensive, you have to take into account the hassle of injections and traveling with the medication.
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Lialda (Mesalamine) is an anti-inflammatory medication. Researchers don't know exactly how Lialda (Mesalamine) works in the colon, but it seems to lower the chemicals in the body that cause inflammation.
Humira (Adalimumab) is a biologic response modifier. It works in the immune system to block a protein called TNF (tumor necrosis factor). Blocking TNF relieves symptoms and prevents disease progression.
› Lialda (Mesalamine) is broken down by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need to take a different dose of the medication.
› Rarely, Lialda (Mesalamine) can cause liver injury, hepatitis, and liver failure. Let your doctor know and get medical attention if you notice yellowing skin or eyes.
No kidneys and liver related info.
Upsides and benefits
› Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
› About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
› Available in tablets, capsules, enemas, and suppositories.
› Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
› Treats certain types of arthritis and gastrointestinal conditions caused by an overactive immune system.
› Most people feel it's worth the hassle.
› Once you've learned the correct way to use Humira, you can inject the medicine yourself without going to your doctor's office.
› It's available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
› It's an alternative for people with Crohn's disease who stopped getting better on other TNF-blockers or had side effects that made them switch.
Downsides and risks
› No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
› Doesn't work well for severe colon inflammation.
› You may need to take Lialda (Mesalamine) three or four times a day.
› Not a good option if you have kidney disease.
› It's an injection.
› It's expensive because there's no generic available yet.
› Humira lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
› You're first dose of Humira will need to be given at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
› You'll need to properly dispose of the needle, syringes, or Pen in a special (FDA-approved) sharps container.
› Because it needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.
Tips from our pharmacists for people taking the medication
› Don't take Lialda (Mesalamine) if you're allergic to aspirin. Talk to your doctor or pharmacist about any drug allergies you have before starting Lialda (Mesalamine).
› Taking antacids with Lialda (Mesalamine) can make your inflammation worse. Talk to your doctor before you make any changes.
› You can sunburn more easily when taking Lialda (Mesalamine). Use sunscreen and protective clothing when you go outdoors.
› Don't break, chew, or crush the tablets because they're coated and won't work as well.
› The suppositories should be kept in for at least 1 to 3 hours to get the most benefit.
› Humira (Adalimumab) is a medication that's injected under the skin (subcutaneous). Your doctor can give you your first dose, then let you self-inject it once so you learn how to do it correctly.
› Humira (Adalimumab) lowers the your immune system's ability to fight infections, so it's important to let your doctor know if you come down with a fever, cough, or notice flu-like symptoms.
› You'll need to have a TB test before you start using Humira (Adalimumab).
› Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
› Don't inject Humira (Adalimumab) into skin that's red, bruised, or irritated. Rotate your injection areas to avoid skin reactions.
› As with all injection medicines, store away from children and throw used syringes away in a protective container, and not in the trash.