Compare Asacol vs. Humira

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lialda (Mesalamine)

Prescription only

Humira (adalimumab)

Prescription only
Treats inflammatory bowel disease.

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

Calms down the immune system.

Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.

3.6/ 5 average rating with 182 reviewsforHumira
Upsides
  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
  • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
  • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
  • Humira (adalimumab) treats many different autoimmune conditions.
  • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
Downsides
  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
  • Not first-choice treatment for rheumatoid arthritis.
  • Humira (adalimumab) is an injection and not an oral medication.
  • Humira (adalimumab) is expensive because there's no generic available yet.
  • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
  • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
Used for
Dosage forms
  • Pill
  • Extended release
  • Enema
  • Suppository
  • Injection
Price
Lowest price
$4537.05
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Reviews
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182 reviews so far
60%
saidit'sworth it
51%
saiditworked well
26%
saidit'sa big hassle

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Side effects
35possible side effects
  • Headache
    35%
  • Abdominal pain
    18%
  • Eructation
    16%
  • Pain
    14%
  • Nausea
    13%
  • Pharyngitis
    11%
  • Dizziness
    8%
  • Asthenia
    7%
  • Diarrhea
    7%
  • Back pain
    7%
  • Fever
    6%
  • Rash
    6%
  • Dyspepsia
    6%
  • Rhinitis
    5%
  • Arthralgia
    5%
  • Hypertonia
    5%
  • Vomiting
    5%
  • Constipation
    5%
  • Flatulence
    3%
  • Dysmenorrhea
    3%
  • Chest pain
    3%
  • Chills
    3%
  • Flu syndrome
    3%
  • Peripheral edema
    3%
  • Myalgia
    3%
  • Sweating
    3%
  • Colitis exacerbation
    3%
  • Pruritus
    3%
  • Adverse events
    3%
  • Acne
    2%
  • Increased cough
    2%
  • Malaise
    2%
  • Arthritis
    2%
  • Conjunctivitis
    2%
  • Insomnia
    2%
See more detailed side effects
14possible side effects
  • Upper airway infection
    17%
  • Headache
    12%
  • Rash
    12%
  • Sinus infection
    11%
  • Nausea
    9%
  • Injection site reactions
    8%
  • Urinary tract infection
    8%
  • Flu syndrome
    7%
  • Stomach pain
    7%
  • High cholesterol
    7%
  • Back pain
    6%
  • Blood in urine
    5%
  • Abnormal liver tests
    5%
  • High blood pressure
    5%
See more detailed side effects
Risks and risk factors
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Serious allergic reactions
    • Phenylketonuria (PKU)
  • Worsening kidney or liver function
    • Kidney problems
    • Liver problems
  • Blood disorders
    • Age 65 or older
  • Liver toxicity
    • Liver problems
  • Worsening of colitis
    • Taking Lialda (Mesalamine) at the start of treatment
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant medications such as Kineret or Orencia
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
  • Cancers
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
    • History of malignancy
    • Adolescent age
    • COPD with significant smoking history
  • Serious allergic reactions
  • Heart problems
    • History of heart failure
  • Nervous system effects
    • Preexisting or recently acquired neurologic condition
  • Lower blood cell counts
See more detailed risks and warnings