Compare Asmanex vs. Flonase

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Prevents breathing problems. Asmanex (Mometasone) is good at controlling and preventing asthma symptoms when you take it every day.Relieves allergy symptoms. Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Asmanex (Mometasone)
of people say Asmanex (Mometasone) is worth it
say it works well
say it's a big hassle
Reviews for Flonase (Fluticasone)
+17% vs. Asmanex (Mometasone)
+4% vs. Asmanex (Mometasone)
+13% vs. Asmanex (Mometasone)
Side effects
  • Allergic rhinitis 15%
  • Candidiasis, oral 13%
  • Fatigue 11%
  • Musculoskeletal pain 8%
  • Sore throat 6%
  • Joint pain 6%
  • Menstrual cramps 5%
  • Abdominal pain 4%
  • Sinus inflammation 3%
  • Fever 2%
More Asmanex side effects »
  • Asthma symptoms 4%
  • Nausea/vomiting 3%
  • Nosebleed 2%
  • Headache 1%
  • Cough 1%
  • Sore throat 1%
More Flonase side effects »
How it works
Asmanex (Mometasone) is a corticosteroid. It lowers inflammation in your lungs, which controls asthma and prevents asthma attacks.Flonase (Fluticasone) is a nasal steroid. It works directly in your nose to reduce swelling and inflammation caused by allergies.
Type of medication
Prescription only
Prescription or OTC
Available as
  • Inhaler
  • Nasal spray
Used for (click to learn more)
Risk factors for serious side effects
  • Lowering dose or stopping Asmanex (Mometasone) too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Severe milk protein allergy
  • Bacterial or viral infection not being treated
  • Long-term treatment with Asmanex (Mometasone)
  • Not vaccinated against chickenpox or measles
    • Dose of Asmanex (Mometasone)
    • Duration of treatment
    • Not rinsing mouth after use
    • Using higher dose of Asmanex (Mometasone)
    • History of high internal eye pressure
    • History of cataracts
    • History of glaucoma
    Detailed Asmanex (Mometasone) risks & warnings »
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)
      • Long-term use
      • Taking more than recommended dose
      • Switching from oral or injectable steroids to inhaled, especially if used long term
      • Using other inhaled steroids with Flonase (Fluticasone)
      • Long-term use
      • Exposure to immunizable diseases (chickenpox and measles)
      • Exposure to tuberculosis
      • Surgery or trauma to the nose or sinuses
      • Long-term use
      Detailed Flonase (Fluticasone) risks & warnings »
      Pregnancy category
      No specific alcohol-related info.No specific alcohol-related info.
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      No specific sleep-related info.No specific sleep-related info.
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      • Relieves symptoms and improves control of asthma.
      • People report fewer asthma symptoms and better lung function when they take it every day.
      • Inhaling this medicine (rather than taking an oral steroid) gets more into the lungs and less into rest of your body, which lowers the risk of side effects. Inhaled corticosteroids can be used safely for years compared to oral corticosteroids like prednisone.
      • Some people who take this medicine are able to stop other asthma medications or use their fast-acting (rescue) inhalers less often.
      • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
      • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
      • Can be used as needed to help control symptoms in people age 13 years or older.
      • Available as a generic medication.
      Downsides and risks
      • You can't lower the dose or stop taking it too suddenly.
      • Steroids can slow height growth in kids.
      • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
      • Can cause new or worsening eye pressure, glaucoma, and cataracts.
      • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
      • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
      • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
      Tips from our pharmacists for people taking the medication
      • Use it every day to control your asthma symptoms.
      • Starts working the same day, but it can take 1 to 2 weeks to feel the full effects.
      • Rinse your mouth out with water after each use.
      • Replace the cap on the inhaler after each use to protect it from moisture.
      • Hold your breath for 10 seconds after inhaling the medication.
      • Don't breathe out into the inhaler mouthpiece.
      • Tell your doctor if the medication stops working or if your symptoms get worse.
      • Contains lactose, so don't take if you have a milk protein allergy.
      • It can take several days for Flonase (Fluticasone) to start working fully.
      • Don't take more of it than was prescribed for you.
      • Blow your nose before using Flonase (Fluticasone).
      • Can cause thrush (a fungal infection) inside the nose and throat.
      • Can also cause a headache, sore throat, or nosebleeds.
      Learn more
      More about AsmanexSide effectsReviews & ratingsAlternativesFDA package insert
      More about FlonaseSide effectsReviews & ratingsAlternativesFDA package insert