Compare Asmanex vs. Singulair

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prevents breathing problems. Asmanex (Mometasone) is good at controlling and preventing asthma symptoms when you take it every day.Prevents breathing problems. Singulair (Montelukast) has fewer side effects but doesn't work as well as steroid inhalers for asthma. It also helps with allergies.
How it works
Asmanex (Mometasone) is a corticosteroid. It lowers inflammation in your lungs, which controls asthma and prevents asthma attacks.Singulair (Montelukast) is a leukotriene inhibitor. It lowers inflammation in your lungs and nasal passages to prevent asthma and relieve allergies.
Type of medication
Prescription only
Leukotriene modifier
Prescription only
Available as
  • Inhaler
  • Pill
  • Chewable tablet
  • Granule
Used for (click to learn more)
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Asmanex (Mometasone)
of people say Asmanex (Mometasone) is worth it
say it works well
say it's a big hassle
Reviews for Singulair (Montelukast)
+11% vs. Asmanex (Mometasone)
+7% vs. Asmanex (Mometasone)
+7% vs. Asmanex (Mometasone)
Side effects
  • Allergic rhinitis 15%
  • Candidiasis, oral 13%
  • Fatigue 11%
  • Musculoskeletal pain 8%
  • Sore throat 6%
  • Joint pain 6%
  • Menstrual cramps 5%
  • Abdominal pain 4%
  • Sinus inflammation 3%
  • Fever 2%
More Asmanex side effects »
  • Dizziness 1%
  • Muscle weakness/fatiguea/fatigue 1%
  • Decreased liver function 1%
  • Congestion, nasal 1%
  • Pain, dental 1%
More Singulair side effects »
Risk factors for serious side effects
  • Lowering dose or stopping Asmanex (Mometasone) too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Severe milk protein allergy
  • Bacterial or viral infection not being treated
  • Long-term treatment with Asmanex (Mometasone)
  • Not vaccinated against chickenpox or measles
    • Dose of Asmanex (Mometasone)
    • Duration of treatment
    • Not rinsing mouth after use
    • Using higher dose of Asmanex (Mometasone)
    • History of high internal eye pressure
    • History of cataracts
    • History of glaucoma
    Detailed Asmanex (Mometasone) risks & warnings »
    • Exercise-induced asthma
    • Other environmental triggers
      • Recent treatment with corticosteroid medication
      • Lowering dose of corticosteroid medication
      • History of phenylketonuria (PKU)
      • History of liver disease including hepatitis
      • history of alcohol use
      • Other medications that cause liver injury
      Detailed Singulair (Montelukast) risks & warnings »
      Pregnancy category
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      No specific alcohol-related info.
      • There are reports of liver injury in people taking Singulair (Montelukast) mostly in combination with other factors such as drugs, alcohol, and liver disease. If you have any of these risk factors, your doctor will need to check your liver function periodically.
      No specific food-related info.
      • Granules can be taken by mouth or dissolved in liquid or soft food.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      No specific sleep-related info.
      • Can cause behavior changes, agitation, aggression, and difficulty sleeping for some people.
      • Rare cases of behavior changes occur in adults and children taking Singulair (Montelukast). Symptoms range from irritability and memory problems to hallucinations and suicidal thinking. It is not clear if this is linked to history of these conditions. Get medical help immediately if you notice symptoms of agitation, aggression, sleep disturbance, or suicidal thoughts while taking Singulair (Montelukast).
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      • Relieves symptoms and improves control of asthma.
      • People report fewer asthma symptoms and better lung function when they take it every day.
      • Inhaling this medicine (rather than taking an oral steroid) gets more into the lungs and less into rest of your body, which lowers the risk of side effects. Inhaled corticosteroids can be used safely for years compared to oral corticosteroids like prednisone.
      • Some people who take this medicine are able to stop other asthma medications or use their fast-acting (rescue) inhalers less often.
      • Prevents symptoms and improves lung function in children and adults with chronic asthma.
      • A single 10 mg dose improves exercise-induced asthma symptoms for up to 24 hours.
      • Fewer side effects compared to other asthma treatments.
      • Also relieves nasal allergy symptoms.
      • Effective pill alternative to corticosteroid inhalers.
      Downsides and risks
      • You can't lower the dose or stop taking it too suddenly.
      • Steroids can slow height growth in kids.
      • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
      • Can cause new or worsening eye pressure, glaucoma, and cataracts.
      • You have to use Montelukast every day to control your symptoms.
      • Somewhat less effective than corticosteroid inhalers for asthma.
      • There's no generic available, so it can be expensive.
      • Can cause behavior changes, agitation, aggression, and difficulty sleeping for some people.
      Tips from our pharmacists for people taking the medication
      • Use it every day to control your asthma symptoms.
      • Starts working the same day, but it can take 1 to 2 weeks to feel the full effects.
      • Rinse your mouth out with water after each use.
      • Replace the cap on the inhaler after each use to protect it from moisture.
      • Hold your breath for 10 seconds after inhaling the medication.
      • Don't breathe out into the inhaler mouthpiece.
      • Tell your doctor if the medication stops working or if your symptoms get worse.
      • Contains lactose, so don't take if you have a milk protein allergy.
      • Take it once a day to control asthma and allergy symptoms.
      • If you're using it for asthma or allergies, take it in the evening.
      • Use it 2 hours before exercising.
      • Granules can be taken by mouth or dissolved in liquid or soft food.
      • Doesn't treat sudden wheezing or asthma attacks once they start. Keep a fast-acting (rescue) inhaler with you.
      • The chewable tablets contain aspartame, so don't use them if you have a sensitivity to phenylalanine or phenylketones.
      Learn more
      More about AsmanexSide effectsReviews & ratingsAlternativesFDA package insert
      More about SingulairSide effectsReviews & ratingsAlternativesFDA package insert