Compare Aspirin vs. Celebrex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aspirin

Celebrex
(Celecoxib)

Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.Relieves pain and inflammation. Celebrex (Celecoxib) works well for treating pain and causes less upset stomach than other NSAIDs.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.152255639097745Aspirin
Reviews for Aspirin
76%
of people say Aspirin is worth it
41%
say it works well
6%
say it's a big hassle
Reviews for Celebrex (Celecoxib)
56%
20% vs. Aspirin
36%
5% vs. Aspirin
13%
7% vs. Aspirin
Side effects
AspirinCelebrex

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »

We haven’t found good data for Celebrex side effects.

FDA side effect reports for Celebrex »
How it works
AspirinCelebrex
Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.Celebrex (Celecoxib) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.
Type of medication
AspirinCelebrex
Pain reliever
Salicylate
Anticoagulant
Anti-platelet
Over-the-counter
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription only
Available as
AspirinCelebrex
  • Pill
  • Pill
Used for (click to learn more)
AspirinCelebrex
Risk factors for serious side effects
AspirinCelebrex
  • Children 18 years or younger
  • Children recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking Aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Women of childbearing age
Detailed Aspirin risks & warnings »
  • Long-term use
  • History of heart disease
  • History of heart bypass surgery (coronary artery bypass graft/CABG)
  • Age 65 or older
  • History of GI bleed or peptic ulcer disease
  • History of high blood pressure
  • Taking water pills (diuretics)
  • History of heart failure
    • History of asthma
    • Kidney Disease
    • Heart Failure
    • Liver Disease
    • Also taking diuretics
    • Also taking ACE inhibitors
    • Also taking Angiotensin Receptor Blockers (ARBs)
    • Age 65 or older
    • Late pregnancy (more than 30 weeks)
    Detailed Celebrex (Celecoxib) risks & warnings »
    Pregnancy category
    AspirinCelebrex
    NFDA pregnancy category (Unknown)

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    • Take with food to lower the chance of an upset stomach.
    • Take it with a meal or a snack to prevent an upset stomach.
    Kidneys and liver
    No specific kidneys and liver-related info.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Celebrex (Celecoxib), and similar medications in the NSAID family, can cause lower kidney function or cause permanent kidney damage. You're at higher risk for this if you've a history of kidney disease, heart failure, and liver disease. Taking Diuretic, ACE inhibitor, or Angiotensin Receptor Blocker (ARB) medications also increases your risk. If you are 65 or older you're also at a higher risk for these types of kidney problems.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    AspirinCelebrex
    • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
    • Used in higher doses to relieve pain, swelling, and fever.
    • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
    • Relieves pain and inflammation for many types of arthritis, including osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
    • Good for treating muscle aches and pains, as well as menstrual cramps.
    • Causes fewer stomach problems than other NSAIDs like Ibuprofen or Naproxen.
    • Lasts longer than Ibuprofen.
    Downsides and risks
    AspirinCelebrex
    • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
    • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
    • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
    • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
    • The longer you take Celebrex (Celecoxib), the more likely you are to have stomach problems, including inflammation, ulcers, and bleeding. Can also happen if you take Celebrex (Celecoxib) on an empty stomach.
    • Like all NSAIDs, it can raise your risk of blood clots, heart attack, or a stroke.
    • Can also affect your kidneys or cause permanent kidney damage if taken for a long time.
    Tips from our pharmacists for people taking the medication
    AspirinCelebrex
    • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
    • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
    • Take with food to lower the chance of an upset stomach.
    • Don't use for kids younger than 18 years old.
    • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
    • Starts working in 1 to 3 hours.
    • Take it with a meal or a snack to prevent an upset stomach.
    • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
    • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    Learn more
    More about AspirinSide effectsReviews & ratingsAlternativesFDA package insert
    More about CelebrexSide effectsReviews & ratingsAlternativesFDA package insert