Compare Aspirin vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

aspirin

Coumadin
(warfarin)

Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.Prevents blood clots. Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.
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Prices and coupon for 30 (81mg) tablets of aspirin
Coupons for
Prices and coupon for 30 (5mg) tablets of warfarin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.15Aspirin
Reviews for Aspirin
76%
of people (All ages) say Aspirin is worth it
41%
say it works well
6%
say it's a big hassle
533 reviews
Have you used Aspirin?
Worth itNot sureNot worth it
Reviews for Coumadin (warfarin)
61%
-15% worse vs. Aspirin
54%
+13% better vs. Aspirin
21%
-15% worse vs. Aspirin
513 reviews
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it
Side effects
AspirinCoumadin

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »
How it works
AspirinCoumadin
Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.Coumadin (warfarin) prevents blood clots from forming. It doesn't break up clots that already exist. It can only stop new ones from forming or old ones from getting bigger.
Type of medication
AspirinCoumadin
Over-the-counter
Prescription only
Available as
AspirinCoumadin
  • Pill
  • Pill
Used for
AspirinCoumadin
Risk factors for serious side effects
AspirinCoumadin
  • Children 18 years or younger
  • Children recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking Aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Women of childbearing age
Detailed Aspirin risks & warnings »
  • Coumadin (warfarin) dose too high
  • Age greater than 65 year
  • History of stomach bleeding
  • High blood pressure
  • Kidney or liver problems
  • Drug interactions
  • Change in lifestyle or diet
  • Alcohol use
  • Certain genetic factors
  • Women of childbearing age
      Detailed Coumadin (warfarin) risks & warnings »
      Pregnancy

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      Interactions
      AspirinCoumadin
      No interactions related info.
      • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
      • Coumadin (warfarin) interacts with many drugs and supplements. This can increase your risk of bleeding or of developing a new blood clot. If you start a new medication or change your diet, let your doctor know so they can change your dose if necessary.
      Food
      AspirinCoumadin
      • Take with food to lower the chance of an upset stomach.
      No food related info.
      Pain
      AspirinCoumadin
      • Used in higher doses to relieve pain, swelling, and fever.
      No pain related info.
      Upsides and benefits
      AspirinCoumadin
      • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
      • Used in higher doses to relieve pain, swelling, and fever.
      • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
      • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
      • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
      • Coumadin (warfarin) comes in numerous strengths.
      • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
      Downsides and risks
      AspirinCoumadin
      • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
      • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
      • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
      • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
      • Raises your risk of bleeding and bruising.
      • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
      • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
      • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
      Tips from our pharmacists for people taking the medication
      AspirinCoumadin
      • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
      • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
      • Take with food to lower the chance of an upset stomach.
      • Don't use for kids younger than 18 years old.
      • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
      • Prevents clots from forming or getting bigger. It doesn't break up clots that already exist.
      • Take Coumadin (warfarin) exactly as your doctor tells you.
      • Once you're taking Coumadin (warfarin), it'll take longer for your body to heal if you get cut or bruised. Call your doctor if you notice any unusual bleeding or bruising.
      • Carry a list of your medications with you or wear a medical bracelet that says you're on Coumadin (warfarin) in case you have a medical emergency.
      • Your doctor will check your blood regularly for the first few months that you're taking Coumadin (warfarin).
      • To get the best results, don't fall behind on taking your other medicines and eat the same amount of vegetables each day.
      Learn more
      More about AspirinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Aspirin?
      Worth itNot sureNot worth it
      More about CoumadinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Coumadin (warfarin)?
      Worth itNot sureNot worth it