Compare Aspirin vs. Lovenox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

aspirin

Lovenox
(enoxaparin)

Relieves pain, fever, and inflammation. Protects your heart and thins blood. A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.Prevents blood clots. Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.15Aspirin
Reviews for Aspirin
76%
of people (All ages) say Aspirin is worth it
41%
say it works well
6%
say it's a big hassle
533 reviews
Have you used Aspirin?
Worth itNot sureNot worth it
Reviews for Lovenox
63%
+13% better vs. Aspirin
63%
-22% worse vs. Aspirin
16%
+10% better vs. Aspirin
Have you used Lovenox (enoxaparin)?
Worth itNot sureNot worth it
Side effects
AspirinLovenox

We haven’t found good data for Aspirin side effects.

FDA side effect reports for Aspirin »
  • Injection site hematoma 7%
  • Hemorrhage 7%
  • Major hemorrhage 4%
  • Nausea 1%
  • Confusion 1%
  • Fever 2%
More Lovenox side effects »
How it works
AspirinLovenox
Aspirin is a salicylate and non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain. It also prevents blood platelets from forming clots, which thins your blood.Lovenox (Enoxaparin) is an anticoagulant that prevents certain blood-clotting proteins from working. By stopping blood clots from forming, there's a lower chance of having a stroke or blood clots travel to your lungs.
Type of medication
AspirinLovenox
Over-the-counterPrescription only
Available as
AspirinLovenox
  • Pill
  • Injection
Used for
AspirinLovenox
Risk factors for serious side effects
AspirinLovenox
  • Children 18 years or younger
  • Children recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking Aspirin, NSAIDs, or blood thinners
Detailed Aspirin risks & warnings »
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • Taking NSAIDs or other blood thinning medicines
  • History of bleeding problems
  • Severe high blood pressure
Detailed Lovenox (enoxaparin) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Food
AspirinLovenox
  • Take with food to lower the chance of an upset stomach.
  • Available in generic so it can be cheaper than other "blood thinners".
Pain
AspirinLovenox
  • Used in higher doses to relieve pain, swelling, and fever.
No pain related info.
Upsides and benefits
AspirinLovenox
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
Downsides and risks
AspirinLovenox
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
Tips from our pharmacists for people taking the medication
AspirinLovenox
  • Using low doses (81mg) of Aspirin every day can lower your risk of heart attack and stroke, but it isn't good for everyone. Only take Aspirin daily if your doctor recommends it.
  • Higher Aspirin doses can be used to treat occasional pain, swelling, and fever. Using ibuprofen or acetaminophen (Tylenol) instead can lower your risk of serious bleeding.
  • Take with food to lower the chance of an upset stomach.
  • Don't use for kids younger than 18 years old.
  • Stop taking this right away and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that doesn't go away.
  • Rotate the spot where you inject Lovenox (Enoxaparin) every day.
  • While on this, it can take longer to stop bleeding and you are more likely to bruise or bleed more easily.
  • Avoid taking certain anti-inflammatory drugs (like NSAIDs) because they can make you more likely to bleed.
  • Can cause swelling in your legs, diarrhea, and nausea.
Learn more
More about AspirinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Aspirin?
Worth itNot sureNot worth it
More about LovenoxSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lovenox (enoxaparin)?
Worth itNot sureNot worth it