Compare Aspirin vs. Lovenox

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aspirin

Over-the-counter

Lovenox (Enoxaparin)

Prescription only
Relieves pain, fever, and inflammation. Protects your heart and thins blood.

A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.

3.8/ 5 average rating with 533 reviewsforAspirin
Prevents blood clots.

Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.

4.0/ 5 average rating with 19 reviewsforLovenox
Upsides
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
  • In a study that compared Lovenox (Enoxaparin) to other medications used to stop blood clots, there was a lower risk of clots coming back, with similar rates of major bleeding and mortality.
  • You don't need to go in for lab tests to check whether it's working, unlike other medications like warfarin that require regular blood draws.
  • Available in generic so it can be cheaper than other "blood thinners".
  • Good option if you're pregnant or have cancer.
Downsides
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
  • It is only available as an injection, so it's not great if you're afraid of needles.
  • While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
  • It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.
Used for
Dosage forms
  • Pill
  • Injection
Price
No pricing information available
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Reviews
533 reviews so far
76%
saidit'sworth it
41%
saiditworked well
6%
saidit'sa big hassle

Have you used Aspirin?

Leave a review
19 reviews so far
63%
saidit'sworth it
63%
saiditworked well
16%
saidit'sa big hassle

Have you used Lovenox (Enoxaparin)?

Leave a review
Side effects
The Aspirin FDA package insert doesn’t have numbers about how common side effects are.
7possible side effects
  • Fever
    5%
  • Major hemorrhage
    4%
  • Hemorrhage
    4%
  • Nausea
    3%
  • Peripheral edema
    3%
  • Anemia
    2%
  • Edema
    2%
See more detailed side effects
Risks and risk factors
  • Brain damage or death from Reye's Syndrome
    • Children 18 years or younger
    • Children recovering from viral infections
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking Aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Harm to unborn babies
    • Women of childbearing age
See more detailed risks and warnings
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • Taking NSAIDs or other blood thinning medicines
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Older age
  • Increased risk of stroke or increased risk of blood clots
    • Stopping Lovenox (Enoxaparin) early
  • Clotting problems
    • Heparin-induced thrombocytopenia
See more detailed risks and warnings