Compare Astepro vs. Afrin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Astepro (Azelastine) is a prescription-only antihistamine nasal spray that can help with your allergy or nasal symptoms without exposing the rest of your body to the medicine.
Afrin (oxymetazoline) clears stuffy noses, but can worsen your congestion if it is used more frequently than 3 days in a row.
- Astepro (Azelastine) lowers the number of nasal symptoms you'll get during allergy season.
- Works faster than steroid nasal sprays and can be used as needed.
- Most people don't have any side effects since it works in the nose and doesn't affect the rest of your body.
- Won't make you feel sleepy.
- Works just as well as steroid nasal sprays.
- It works right away and each dose lasts up to 12 hours.
- The effect is limited to your nasal passageways so it may be safer than other decongestants you take orally.
- Available as a nasal spray and a nasal mist.
- Can be purchased over-the-counter without a prescription.
- In older versions of the medicine, you can get a bitter taste in your mouth after spraying it into your nose.
- Can cause nose bleeds if the spray nozzle is inserted into your nose wrongly.
- Need a prescription to get Astepro (Azelastine).
- It's good for 200 sprays, but there isn't a counter to help you keep track of sprays.
- Sometimes Afrin (oxymetazoline) causes temporary stinging, burning, or dryness of the nose.
- Talk to your doctor first before using it in children younger than 6 years old.
- Nasal spray
- Nasal spray
- Driving impairment
Taking with alcohol
...and 1 more risk factors
- Rebound nasal congestion
Using Afrin (oxymetazoline) for more than 3 days