Compare Astepro vs. prednisolone acetate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Astepro (Azelastine)

Prescription only
Relieves nasal allergy symptoms.

Astepro (Azelastine) is a prescription-only antihistamine nasal spray that can help with your allergy or nasal symptoms without exposing the rest of your body to the medicine.

Calms down redness and swelling in the eye.

Omnipred (prednisolone acetate) is a steroid used in the eye that is effective for treatment and symptom relief, but with long-term use, it can have some side effects.

Upsides
  • Astepro (Azelastine) lowers the number of nasal symptoms you'll get during allergy season.
  • Works faster than steroid nasal sprays and can be used as needed.
  • Most people don't have any side effects since it works in the nose and doesn't affect the rest of your body.
  • Won't make you feel sleepy.
  • Works just as well as steroid nasal sprays.
  • Omnipred (prednisolone acetate) works only within the eye, so it will relieve symptoms without having the side effects of oral steroids.
  • Kicks in relatively quickly to relieve symptoms.
  • Available in generic form.
Downsides
  • In older versions of the medicine, you can get a bitter taste in your mouth after spraying it into your nose.
  • Can cause nose bleeds if the spray nozzle is inserted into your nose wrongly.
  • Need a prescription to get Astepro (Azelastine).
  • It's good for 200 sprays, but there isn't a counter to help you keep track of sprays.
  • Depending on the condition, you might have to use Omnipred (prednisolone acetate) up to 4 times a day, particularly in the beginning.
  • If using Omnipred (prednisolone acetate) long-term, may require some monitoring by your doctor.
  • Contains sulfite, so depending on the severity of your allergy, may not be suitable for those with allergies to sulfite.
  • Long-term use can lead to increased risk of more serious side effects.
Used for
  • Inflammation of the Eye
  • Eye Injury
  • Allergies
Dosage forms
  • Nasal spray
  • Liquid
Price
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Reviews
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Side effects
4possible side effects
  • Rhinitis
    17%
  • Cough
    11%
  • Conjunctivitis
    5%
  • Asthma
    5%
See more detailed side effects
The Omnipred (prednisolone acetate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Glaucoma and cataracts
  • Increased risk of infection
  • Thinning of eye layer
  • Severe allergic reactions
    • Asthma
See more detailed risks and warnings