Compare Astepro vs. prednisolone acetate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Astepro
(azelastine)

Omnipred
(prednisolone acetate)

Relieves nasal allergy symptoms. Astepro (Azelastine) is a prescription-only antihistamine nasal spray that can help with your allergy or nasal symptoms without exposing the rest of your body to the medicine.Calms down redness and swelling in the eye. Omnipred (prednisolone acetate) is a steroid used in the eye that is effective for treatment and symptom relief, but with long-term use, it can have some side effects.
Reviews & ratings
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Have you used Astepro (azelastine)?
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Have you used Omnipred (prednisolone acetate)?
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Side effects
Asteproprednisolone acetate
  • Bitter Taste 19%
  • Headache 2%
  • Somnolence 7%
  • Pharyngitis 1%
  • Nasal Burning 2%
  • Nasal Discomfort 4%
  • Paroxysmal Sneezing 2%
  • Dry Mouth 1%
  • Nausea 2%
More Astepro side effects »

The prednisolone acetate FDA package insert doesn’t have numbers about how common side effects are.

More about prednisolone acetate side effects »
How it works
Asteproprednisolone acetate
Astepro (Azelastine) is an antihistamine nasal spray. It works directly in your nose to block histamine, a chemical that causes runny nose, itching, and sneezing.Prednisolone acetate is a steroid that is similar to your body's natural steroids. It reduces swelling in the eye and alleviates pain, discomfort, or harm.
Type of medication
Asteproprednisolone acetate
Prescription onlyPrescription only
Available as
Asteproprednisolone acetate
  • Nasal spray
  • Liquid
Used for
Asteproprednisolone acetate
  • Inflammation Of The Eye
Risk factors for serious side effects
Asteproprednisolone acetate
  • Taking with alcohol
  • Taking other medicines that make you less alert
Detailed Astepro (azelastine) risks & warnings »
  • Asthma
Detailed Omnipred (prednisolone acetate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Price
Asteproprednisolone acetate
  • It's good for 200 sprays, but there isn't a counter to help you keep track of sprays.
No price related info.
Pain
Asteproprednisolone acetate
No pain related info.
  • If inflammation or pain gets worse or lasts longer than 2 days while taking Omnipred (prednisolone acetate), talk to your doctor.
Sleep
Asteproprednisolone acetate
  • Won't make you feel sleepy.
No sleep related info.
Upsides and benefits
Asteproprednisolone acetate
  • Astepro (Azelastine) lowers the number of nasal symptoms you'll get during allergy season.
  • Works faster than steroid nasal sprays and can be used as needed.
  • Most people don't have any side effects since it works in the nose and doesn't affect the rest of your body.
  • Won't make you feel sleepy.
  • Works just as well as steroid nasal sprays.
  • Omnipred (prednisolone acetate) works only within the eye, so it will relieve symptoms without having the side effects of oral steroids.
  • Kicks in relatively quickly to relieve symptoms.
  • Available in generic form.
Downsides and risks
Asteproprednisolone acetate
  • In older versions of the medicine, you can get a bitter taste in your mouth after spraying it into your nose.
  • Can cause nose bleeds if the spray nozzle is inserted into your nose wrongly.
  • Need a prescription to get Astepro (Azelastine).
  • It's good for 200 sprays, but there isn't a counter to help you keep track of sprays.
  • Depending on the condition, you might have to use Omnipred (prednisolone acetate) up to 4 times a day, particularly in the beginning.
  • If using Omnipred (prednisolone acetate) long-term, may require some monitoring by your doctor.
  • Contains sulfite, so depending on the severity of your allergy, may not be suitable for those with allergies to sulfite.
  • Long-term use can lead to increased risk of more serious side effects.
Tips from our pharmacists for people taking the medication
Asteproprednisolone acetate
  • Starts working in 15 minutes.
  • Check with your doctor or pharmacist to make sure you know how to use this nose spray correctly.
  • Before using the spray for the first time, prime it until you see a fine mist.
  • Clear your nose before using the spray and breathe in slowly as you're spraying. After spraying, wait a few minutes before blowing your nose if needed.
  • Tilt your head forward to avoid getting a bitter taste while spraying the medicine.
  • Some people get a headache or feel drowsy and dizzy after using it.
  • If inflammation or pain gets worse or lasts longer than 2 days while taking Omnipred (prednisolone acetate), talk to your doctor.
  • Only a small drop is needed per eye. Tilt your head back and place a drop into your lower eyelid, being careful not to touch the bottle tip to your eyelid or other surface. Afterwards, pinch the top of your nose (in between the eyes) for 15-30 seconds so that the liquid gets absorbed into your eyes.
  • If dose calls for multiple drops, wait 5 minutes in between each drop.
  • Shake well before use. You can store Omnipred (prednisolone acetate) at room temperature, but keeping it in the refrigerator can help alleviate symptoms of pain. Do not freeze.
  • Temporary burning and stinging in the eye may occur after putting in the drop.
  • If you are taking Omnipred (prednisolone acetate) long-term, you may need to gradually stop taking this medication. Take it exactly as your doctor prescribed and do not stop suddenly.
Learn more
More about AsteproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Astepro (azelastine)?
Worth itNot sureNot worth it
More about prednisolone acetateSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Omnipred (prednisolone acetate)?
Worth itNot sureNot worth it