Compare Atenolol vs. Effexor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tenormin
(atenolol)

Effexor
(venlafaxine)

Lowers blood pressure and controls heart rate. Tenormin (atenolol) is good for controlling chest pain and treating a heart attack. It has fewer side effects than other beta blockers. You need to take it on an empty stomach and you can't skip doses.Improves mood and helps you relax. Effexor (Venlafaxine) is good for treating depression and anxiety. It may work when other antidepressants haven't, but it's more likely to cause side effects and withdrawal symptoms than other antidepressants.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.92Atenolol
Reviews for Atenolol
58%
of people (All ages) say Atenolol is worth it
48%
say it works well
16%
say it's a big hassle
457 reviews
Have you used Tenormin (atenolol)?
Worth itNot sureNot worth it
Reviews for Effexor
62%
-4% worse vs. Atenolol
51%
-3% worse vs. Atenolol
23%
+7% better vs. Atenolol
577 reviews
Have you used Effexor (venlafaxine)?
Worth itNot sureNot worth it
Side effects
AtenololEffexor
  • Tiredness 13%
  • Dizziness 7%
  • Depression 3%
  • Cold arms and legs 7%
  • Fatigue 1%
  • Shortness of breath 2%
  • Light-headedness 3%
  • Leg Pain 2%
  • Decreased energy 3%
More Atenolol side effects »
  • Nausea 26%
  • Headache 1%
  • Somnolence 14%
  • Dry mouth 11%
  • Dizziness 11%
  • Insomnia 8%
  • Abnormal Ejaculation 16%
  • Constipation 8%
  • Nervousness 17%
  • Asthenia 14%
More Effexor side effects »
How it works
AtenololEffexor
Tenormin (atenolol) is a selective beta blocker that works specifically on the heart by slowing down the heart and making the heart pump better.Effexor (Venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulate mood.
Type of medication
AtenololEffexor
Prescription onlyPrescription only
Available as
AtenololEffexor
  • Pill
  • Pill
  • Extended release
Used for
AtenololEffexor
Risk factors for serious side effects
AtenololEffexor
  • Suddenly stopping Tenormin (atenolol)
  • Taking calcium channel blockers
  • Major surgery requiring anesthesia
  • Diabetes
  • Taking clonidine
Detailed Tenormin (atenolol) risks & warnings »
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Effexor (Venlafaxine) suddenly
  • History of high blood pressure
  • Taking other blood-thinning drugs
Detailed Effexor (venlafaxine) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Sex
AtenololEffexor
No sex related info.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
Upsides and benefits
AtenololEffexor
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart attack recovery.
  • At lower doses, Tenormin (atenolol) has fewer side effects than other beta blockers because it targets the heart and not other parts of the body.
  • Effective at relieving depression and anxiety symptoms.
  • Lowers relapse rates of depression.
  • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
  • Might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood. Many other antidepressants affect only serotonin, but not norepinephrine too.
Downsides and risks
AtenololEffexor
  • You need to take Tenormin (atenolol) on an empty stomach.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but it might not go away for others.
  • Not a first-choice treatment for high blood pressure unless you have heart disease. However, your doctor could add it to other medicines you're already if your blood pressure is still too high.
  • You can't miss or skip doses. If you stop Tenormin (atenolol) suddenly, it can cause your blood pressure to go up really quickly, raising your risk of heart attack and stroke.
  • Tenormin (atenolol) can hide symptoms of low blood sugar if you're diabetic.
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Not the best option for people with high blood pressure.
  • Overdosing on this medication could be fatal.
  • It's more likely to cause nausea and vomiting or make you feel sick if you miss a dose than other antidepressants. Also causes more sleepiness than others.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Tips from our pharmacists for people taking the medication
AtenololEffexor
  • Lowers bad cholesterol and triglycerides. Raises good cholesterol.
  • Avoid grapefruit and grapefruit juice while taking this medicine.
  • Tell your doctor if you develop sudden muscle pain, fever, or weakness.
  • Tell your doctor if you notice dark urine or yellowing in your eyes or skin.
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
  • Extended-release capsules should be swallowed whole. If you can’t swallow pills, open the capsule, sprinkle it on a spoonful of applesauce and then swallow it without chewing.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
Learn more
More about AtenololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tenormin (atenolol)?
Worth itNot sureNot worth it
More about EffexorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Effexor (venlafaxine)?
Worth itNot sureNot worth it