Compare Ativan vs. Butisol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ativan
(lorazepam)

Butisol
(butabarbital)

Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.Helps you fall asleep. Butisol (butabarbital) is not very good for sleeping problems because it can be addictive.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Ativan
Best available price for 60 (0.5mg) tablets of ativan
Coupons for Butisol
Best available price for 30 (30mg) tablets of butisol
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.14Ativan
Reviews for Ativan
71%
of people (All ages) say Ativan is worth it
51%
say it works well
15%
say it's a big hassle
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Butisol (butabarbital)?
Worth itNot sureNot worth it
Side effects
AtivanButisol
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
  • Sleepiness 3%
More Butisol side effects »
How it works
AtivanButisol
Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.Butisol (butabarbital) is a barbiturate. It works by calming and relaxing you so you're able to sleep.
Type of medication
AtivanButisol
Prescription onlyPrescription only
Available as
AtivanButisol
  • Pill
  • Liquid
  • Injection
  • Pill
Used for
AtivanButisol
Risk factors for serious side effects
AtivanButisol
  • Taking with opioids
  • Taking more than the prescribed dose
  • Taking Ativan (lorazepam) for longer than 4 weeks
  • History of drug abuse
  • Long-term use
Detailed Ativan (lorazepam) risks & warnings »
  • Having acute or chronic pain
  • age 65 or older
  • Drinking alcohol
  • Taking narcotics, tranquilizers or antihistamines
Detailed Butisol (butabarbital) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
AtivanButisol
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
  • Butisol (butabarbital) can interact with a lot of medicines, vitamins and supplements.
Alcohol
AtivanButisol
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Don't drink alcohol or take narcotics, tranquilizers or antihistamines if you're taking Butisol (butabarbital). This can slow down your breathing. Talk to your doctor about other options to help you sleep.
  • Don't drink alcohol or take narcotics with Butisol (butabarbital) since this can slow your breathing.
Pain
AtivanButisol
No pain related info.
  • If you're having acute or chronic pain, or if you're older, Butisol (butabarbital) can cause you to feel more awake instead of sleepy, or you may not notice changes in your pain until it wears off. Talk to your doctor about other options to help you sleep if this happens.
Sleep
AtivanButisol
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
No sleep related info.
Upsides and benefits
AtivanButisol
  • Effective at relieving short-term anxiety.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
  • Butisol (butabarbital) works very quickly to help you fall asleep, within 45-60 minutes, and it lasts 6-8 hours.
Downsides and risks
AtivanButisol
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
  • Most people find that Ativan (lorazepam) gets less effective over time.
  • Your body can get used to needing Butisol (butabarbital) for sleeping.
  • Butisol (butabarbital) can interact with a lot of medicines, vitamins and supplements.
Tips from our pharmacists for people taking the medication
AtivanButisol
  • Can cause temporary dizziness and drowsiness.
  • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
  • Not safe to use with alcohol.
  • Use caution or avoid use in older adults.
  • Don't use Butisol (butabarbital) for more than 2 weeks, since it doesn't work as well after that.
  • Don't stop Butisol (butabarbital) suddenly, especially if you've been taking it for a while. Talk to your doctor about how to get off it safely.
  • Don't drink alcohol or take narcotics with Butisol (butabarbital) since this can slow your breathing.
  • Butisol (butabarbital) can make your birth control less effective. You should use condoms or diaphragms while taking it.
  • Talk to your doctor if Butisol (butabarbital) doesn't help you sleep better after taking it for 7 days.
Learn more
More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
More about ButisolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Butisol (butabarbital)?
Worth itNot sureNot worth it