Compare Ativan vs. chlordiazepoxide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ativan
(lorazepam)

Librium
(chlordiazepoxide)

Helps you relax. Ativan (Lorazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and sleep. Less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.Reduces anxiety. Librium (chlordiazepoxide) is good for lowering anxiety since its effects aren't as strong as similar medicines; however, it lasts longer in the body and can be more dangerous in older people.
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Coupons for Ativan
Best available price for 60 (0.5mg) tablets of lorazepam
Coupons for chlordiazepoxide
Best available price for 60 (25mg) capsules of chlordiazepoxide
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.14Ativan
Reviews for Ativan (lorazepam)
71%
of people (All ages) say Ativan (lorazepam) is worth it
51%
say it works well
15%
say it's a big hassle
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
Reviews for Librium (chlordiazepoxide)
Not enough review data. Review it!
-71% worse vs. Ativan (lorazepam)
Not enough review data. Review it!
-51% worse vs. Ativan (lorazepam)
Not enough review data. Review it!
+15% better vs. Ativan (lorazepam)
Have you used Librium (chlordiazepoxide)?
Worth itNot sureNot worth it
Side effects
Ativanchlordiazepoxide
  • Relaxation or sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »

The chlordiazepoxide FDA package insert doesn’t have numbers about how common side effects are.

More about chlordiazepoxide side effects »
How it works
Ativanchlordiazepoxide
Ativan (Lorazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Librium (chlordiazepoxide) is a benzodiazepine. It's not clear how Librium (chlordiazepoxide) treats anxiety, but it possibly calms activity in a part of the brain that's responsible for emotional responses.
Type of medication
Ativanchlordiazepoxide
Prescription only
Prescription only
Available as
Ativanchlordiazepoxide
  • Pill
  • Liquid
  • Pill
Used for
Ativanchlordiazepoxide
Risk factors for serious side effects
Ativanchlordiazepoxide
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Alcohol
Detailed Ativan (lorazepam) risks & warnings »
  • Taking Librium (chlordiazepoxide) for more than 2 weeks
  • Drinking alcohol or taking narcotics
Detailed Librium (chlordiazepoxide) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Interactions
Ativanchlordiazepoxide
  • Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.
No interactions related info.
Alcohol
Ativanchlordiazepoxide
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Not safe to use with alcohol.
  • Don't drink alcohol or take any narcotics while taking Librium (chlordiazepoxide) since it can slow your breathing.
Sleep
Ativanchlordiazepoxide
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can cause temporary dizziness and drowsiness.
No sleep related info.
Upsides and benefits
Ativanchlordiazepoxide
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.
  • Librium (chlordiazepoxide) is available as a generic.
  • Because Librium (chlordiazepoxide) lasts longer in the body, it's preferred for alcohol withdrawal since it's less likely to cause seizures.
  • Librium (chlordiazepoxide) can be used by itself, or with antidepressants to help lower anxiety.
Downsides and risks
Ativanchlordiazepoxide
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
  • Most people find that it gets less effective over time.
  • Librium (chlordiazepoxide) lasts much longer in older people, so it's not safe to use if you're age 65 or older.
  • Librium (chlordiazepoxide) is not as strong as similar medicines, so it's only really useful to calm anxiety and for alcohol withdrawal.
  • Librium (chlordiazepoxide) can be addictive, so you should use it for as short of a time as possible.
Tips from our pharmacists for people taking the medication
Ativanchlordiazepoxide
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 45 minutes when swallowed.
  • Starts working in 10 to 20 minutes when dissolved under your tongue.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
  • Don't drink alcohol or take any narcotics while taking Librium (chlordiazepoxide) since it can slow your breathing.
  • You should take Librium (chlordiazepoxide) for as short amount of time as possible to treat your anxiety. Librium (chlordiazepoxide) can be addictive.
  • If you've taken Librium (chlordiazepoxide) for a long time, don't stop taking it suddenly without talking to your doctor first. It can be very dangerous.
  • Don't drive or do anything requiring concentration while taking Librium (chlordiazepoxide) since it can make you sleepy. This can be worse if you drink alcohol or take narcotics.
Learn more
More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
More about chlordiazepoxideSide effectsAlternativesFDA package insert
Have you used Librium (chlordiazepoxide)?
Worth itNot sureNot worth it