Compare Ativan vs. Hetlioz

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ativan
(lorazepam)

Hetlioz
(tasimelteon)

Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.Keeps the sleep cycle normal for completely blind people who aren't able to see light. Hetlioz (tasimelteon) is the only approved medicine to help completely blind people who are unable to see light maintain regular sleep cycles. It is only available as a brand name, so it can be expensive.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.14Ativan
Reviews for Ativan
71%
of people (All ages) say Ativan is worth it
51%
say it works well
15%
say it's a big hassle
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it

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Have you used Hetlioz (tasimelteon)?
Worth itNot sureNot worth it
Side effects
AtivanHetlioz
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
  • Headache 10%
  • Abnormal liver tests 5%
  • Nightmares or abnormal dreams 10%
  • Common cold or flu 7%
  • Urinary tract infection 5%
More Hetlioz side effects »
How it works
AtivanHetlioz
Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.Hetlioz (tasimelteon) is a melatonin receptor agonist. It helps you to sleep at night and stay awake during the day.
Type of medication
AtivanHetlioz
Prescription onlyPrescription only
Available as
AtivanHetlioz
  • Pill
  • Liquid
  • Injection
  • Pill
Used for
AtivanHetlioz
  • Non 24 Hour Sleep Wake Cycle
Risk factors for serious side effects
AtivanHetlioz
  • Taking with opioids
  • Taking more than the prescribed dose
  • Taking Ativan (lorazepam) for longer than 4 weeks
  • History of drug abuse
  • Long-term use
Detailed Ativan (lorazepam) risks & warnings »
    Detailed Hetlioz (tasimelteon) risks & warnings »
    Pregnancy
    Interactions
    AtivanHetlioz
    • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
    No interactions related info.
    Alcohol
    AtivanHetlioz
    • Not safe to use with alcohol.
    • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
    No alcohol related info.
    Sleep
    AtivanHetlioz
    • Can cause temporary dizziness and drowsiness.
    • Can cause memory problems, drowsiness, dizziness, and confusion.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    Upsides and benefits
    AtivanHetlioz
    • Effective at relieving short-term anxiety.
    • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
    • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
    • Hetlioz (tasimelteon) is not addictive.
    • Hetlioz (tasimelteon) is the only drug that's approved to help people unable to see light to have regular sleep cycles.
    • If you have to stop taking Hetlioz (tasimelteon) suddenly, you're not likely to have withdrawal.
    Downsides and risks
    AtivanHetlioz
    • Can cause memory problems, drowsiness, dizziness, and confusion.
    • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
    • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
    • Most people find that Ativan (lorazepam) gets less effective over time.
    • Hetlioz (tasimelteon) can take weeks to months for you to notice any effect.
    • Hetlioz (tasimelteon) is only available as a brand name so it can be expensive.
    Tips from our pharmacists for people taking the medication
    AtivanHetlioz
    • Can cause temporary dizziness and drowsiness.
    • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
    • Not safe to use with alcohol.
    • Use caution or avoid use in older adults.
    • Take Hetlioz (tasimelteon) at the same time every night.
    • Take Hetlioz (tasimelteon) on an empty stomach. Swallow capsule whole. Don't crush or chew the capsule.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    • Hetlioz (tasimelteon) might take weeks or months before you notice any effects.
    • If you smoke tobacco, Hetlioz (tasimelteon) might not work as well.
    Learn more
    More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Ativan (lorazepam)?
    Worth itNot sureNot worth it
    More about HetliozSide effectsFDA package insert
    Have you used Hetlioz (tasimelteon)?
    Worth itNot sureNot worth it