Compare Ativan vs. Klonopin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ativan
(Lorazepam)

Klonopin
(Clonazepam)

Helps you relax. Ativan (Lorazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and sleep. Less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.Controls seizures and helps you relax. Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.1035598705501615Ativan
Reviews for Ativan (Lorazepam)
70%
of people say Ativan (Lorazepam) is worth it
50%
say it works well
15%
say it's a big hassle
Reviews for Klonopin (Clonazepam)
69%
1% vs. Ativan (Lorazepam)
51%
+1% vs. Ativan (Lorazepam)
15%
Same vs. Ativan (Lorazepam)
Side effects
AtivanKlonopin

The Ativan FDA package insert doesn’t have numbers about how common side effects are.

More about Ativan side effects »
  • Dizziness 8%
  • Low mood disorder 7%
  • Ear, nose, or throat infection 6%
  • Sinus inflammation 5%
  • Fatigue 5%
  • Menstrual cramps 4%
  • Memory disturbance 3%
  • Constipation 3%
  • Allergic reaction 3%
  • Vaginal inflammation 3%
More Klonopin side effects »
How it works
AtivanKlonopin
Ativan (Lorazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and can cause sleepiness.Klonopin (Clonazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.
Type of medication
AtivanKlonopin
Anti-anxiety
Benzodiazepine
Prescription only
Anti-anxiety
Benzodiazepine
Prescription only
Available as
AtivanKlonopin
  • Pill
  • Liquid
  • Pill
  • Dissolving tablet
Used for (click to learn more)
AtivanKlonopin
Risk factors for serious side effects
AtivanKlonopin
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
    • Alcohol
    • Taking other medicines that make you less alert
      Detailed Ativan (Lorazepam) risks & warnings »
      • Taking more than the prescribed dose
      • Taking longer than 4 weeks
      • History of drug abuse
      • Long-term use
        • Alcohol
        • Taking other medicines that make you less alert
          Detailed Klonopin (Clonazepam) risks & warnings »
          Pregnancy category
          AtivanKlonopin
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
          • Not safe to use with alcohol.
          • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
          • Not safe to use with alcohol.
          Food
          No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          • Can cause memory problems, drowsiness, dizziness, and confusion.
          • Can cause temporary dizziness and drowsiness.
          • Stopping Ativan (Lorazepam) suddenly may cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and muscle pain or burning. Withdrawal symptoms can last 6 weeks or longer. Work with your doctor to gradually reduce your dose.
          • Can cause memory problems, drowsiness, dizziness, and confusion.
          • Can cause dizziness, drowsiness, and salivation.
          • Stopping Klonopin (Clonazepam) suddenly may cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and muscle pain or burning. Withdrawal symptoms can last 6 weeks or longer. Work with your doctor to gradually reduce your dose when stopping or switching to a different medication.
          Weight
          No specific weight-related info.No specific weight-related info.
          Upsides and benefits
          AtivanKlonopin
          • Less likely to have drug interactions compared to other benzodiazepines, so it might be a better option if you're taking multiple medications.
          • Effective at relieving short-term anxiety and sleeplessness.
          • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
          • Can be used alone or with other medicines to treat seizures.
          • Less severe withdrawal symptoms compared to other benzodiazepines.
          • Effective at relieving short-term anxiety and sleeplessness.
          • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
          Downsides and risks
          AtivanKlonopin
          • Compared to other benzodiazepines, more likely to cause withdrawal if you take it for a long time and then stop suddenly.
          • Can cause memory problems, drowsiness, dizziness, and confusion.
          • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
          • Most people find that it gets less effective over time.
          • Can cause memory problems, drowsiness, dizziness, and confusion.
          • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
          • Most people find that it gets less effective over time.
          Tips from our pharmacists for people taking the medication
          AtivanKlonopin
          • Good for short-term relief of anxiety symptoms.
          • Starts working in 45 minutes when swallowed.
          • Starts working in 10 to 20 minutes when dissolved under your tongue.
          • Can cause temporary dizziness and drowsiness.
          • Addictive. Long-term use can cause dependence or abuse.
          • Not safe to use with alcohol.
          • For the first week, avoid activities that require you to be alert.
          • Can cause dizziness, drowsiness, and salivation.
          • Report any confusion or inability to control muscle movements to your doctor.
          • Not safe to use with alcohol.
          Learn more
          More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
          More about KlonopinSide effectsReviews & ratingsAlternativesFDA package insert