Compare Aubagio vs. Avonex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aubagio (Teriflunomide)

Prescription only
Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) is an oral medicine that reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. This medication may not be a good choice if you want to get pregnant.

2.5/ 5 average rating with 23 reviewsforAubagio
Lowers the frequency of multiple sclerosis exacerbations.

Avonex (Interferon Beta-1A) is an injectable medicine effective for relapsing, remitting MS and has manageable side effects and weekly dosing.

2.7/ 5 average rating with 33 reviewsforAvonex
Upsides
  • Aubagio (Teriflunomide) lowers relapses, slows disability, and decreases the number of new brain lesions compared to a sugar pill.
  • You can take Aubagio (Teriflunomide) by mouth.
  • Aubagio (Teriflunomide) only needs to be taken once a day, with or without food.
  • One of the main treatments for relapsing MS that has been around for many years.
  • Injections are given weekly, and not daily like other MS medications.
  • Helps reduce the frequency of MS relapse episodes.
  • Flu-like reactions are the most common side effects and usually go away with continued treatment or can be avoided by using over-the-counter pain and fever-reducing medicines before the injection (like acetaminophen or ibuprofen).
Downsides
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You'll need to have blood tests before and during treatment to make sure you don't have any problems taking Aubagio (Teriflunomide).
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio with an accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or currently take Arava.
  • Injection site reactions are common, ranging from localized pain, redness, and swelling to severe skin dryness.
  • Flu-like symptoms are common after interferon injections.
  • It's not clear what type of problems occur if taken during pregnancy.
  • Blood testing is required before and during use of Avonex (Interferon Beta-1A).
  • May not be as effective as other interferons.
Used for
Dosage forms
  • Pill
  • Injection
Price
Lowest price
$17360.20
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$7018.93
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Reviews
23 reviews so far
43%
saidit'sworth it
26%
saiditworked well
30%
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
33 reviews so far
36%
saidit'sworth it
24%
saiditworked well
33%
saidit'sa big hassle

Have you used Avonex (Interferon Beta-1A)?

Leave a review
Side effects
9possible side effects
  • Headache
    18%
  • Abnormal liver enzymes
    13%
  • Diarrhea
    13%
  • Hair loss
    10%
  • Nausea
    8%
  • Burning or prickling sensation in hands, arms, legs, or feet
    8%
  • Joint pain
    8%
  • Low white blood cells
    4%
  • High blood pressure
    3%
See more detailed side effects
29possible side effects
  • Headache
    57%
  • Flu-like symptoms
    49%
  • Myalgia
    28%
  • Asthenia
    24%
  • Pain
    23%
  • Nausea
    23%
  • Fever
    20%
  • Chills
    19%
  • Depression
    18%
  • Urinary tract infection
    17%
  • Dizziness
    14%
  • Upper respiratory tract infection
    14%
  • Sinusitis
    14%
  • Arthralgia
    9%
  • Abdominal pain
    8%
  • Injection site pain
    8%
  • Bronchitis
    8%
  • Infection
    7%
  • Injuction site inflammation
    6%
  • Injection site ecchymosis
    6%
  • Chest pain
    5%
  • Migraine
    5%
  • Alopecia
    4%
  • Eye disorder
    4%
  • Anemia
    4%
  • Injection site reaction
    3%
  • Toothache
    3%
  • Urine constituents abnormal
    3%
  • Vasodilation
    2%
See more detailed side effects
Risks and risk factors
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Serious allergic reaction
    • Allergy to albumin
    • Prolonged use of Avonex (Interferon Beta-1A)
  • Liver damage
    • Alcohol use
    • Taking drugs that are liver toxic
    • History of liver disease
  • Injection site reaction
  • Heart problems
    • History of heart disease
  • Immune reactions
  • Albumin in the product
  • Seizures
    • History of seizures
  • Risk to fetus
    • Women of childbearing age
  • Bone marrow suppression
See more detailed risks and warnings