Compare Aubagio vs. Betaseron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) is an oral medicine that reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. This medication may not be a good choice if you want to get pregnant.

2.5/ 5 average rating with 23 reviewsforAubagio
Lowers the frequency of MS exacerbations.

Betaseron (Interferon Beta-1B) is an injectable medicine effective for relapsing, remitting MS with fewer side effects and every other day dosing.

3.5/ 5 average rating with 21 reviewsforBetaseron
Upsides
  • Aubagio (Teriflunomide) lowers relapses, slows disability, and decreases the number of new brain lesions compared to a sugar pill.
  • You can take Aubagio (Teriflunomide) by mouth.
  • Aubagio (Teriflunomide) only needs to be taken once a day, with or without food.
  • Interferon beta-1b was the first disease modifying agent for MS approved by the FDA to treat relapsing-remitting multiple sclerosis (RRMS).
  • In short and long-term follow-up studies, Interferon beta-1b was shown to slow MS progression, reduce the number of flair-ups and increase overall survival.
  • Convenient every-other-day dosing and refrigeration-free storage (before mixing) is less of a hassle.
  • Interferon beta-1b has been shown to be more effective than Avonex in reducing new lesions, which lowers relapse and disease progression in people with RRMS.
  • May be a treatment option for people with secondary progressive multiple sclerosis (SPMS).
Downsides
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You'll need to have blood tests before and during treatment to make sure you don't have any problems taking Aubagio (Teriflunomide).
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio with an accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or currently take Arava.
  • Requires injections.
  • Injection site reactions are common. Symptoms range from pain, redness, and swelling to severe reactions with skin death around the injection site.
  • Flu-like symptoms are common after interferon injections, but are less likely with Interferon beta-1b in particular.
  • Blood testing required before and during use based on your other conditions.
  • Unclear consequences to fetus during pregnancy.
Used for
Dosage forms
  • Pill
  • Injection
Price
Lowest price
$17360.20
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Lowest price
$6073.22
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Reviews
23 reviews so far
43%
saidit'sworth it
26%
saiditworked well
30%
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
21 reviews so far
57%
saidit'sworth it
48%
saiditworked well
38%
saidit'sa big hassle

Have you used Betaseron (Interferon Beta-1B)?

Leave a review
Side effects
9possible side effects
  • Headache
    18%
  • Abnormal liver enzymes
    13%
  • Diarrhea
    13%
  • Hair loss
    10%
  • Nausea
    8%
  • Burning or prickling sensation in hands, arms, legs, or feet
    8%
  • Joint pain
    8%
  • Low white blood cells
    4%
  • High blood pressure
    3%
See more detailed side effects
49possible side effects
  • Lymphocytes count decreased (<1500/mm3)
    66%
  • Asthenia
    48%
  • Immunogenicity
    45%
  • Headache
    43%
  • Flu-like symptoms (complex)
    37%
  • Pain
    35%
  • Hypertonia
    33%
  • Injection site reaction
    26%
  • Fever
    19%
  • Leukopenia
    18%
  • Insomnia
    16%
  • Incoordination
    15%
  • Rash
    15%
  • Myalgia
    14%
  • Abdominal pain
    11%
  • Peripheral edema
    10%
  • Chills
    9%
  • Skin disorder
    8%
  • Urinary urgency
    8%
  • Metrorrhagia
    7%
  • Impotence
    6%
  • Chest pain
    6%
  • Absolute neutrophil count decreased (< 1500/mm3)
    5%
  • White blood cell count decreased (<3000/mm3)
    4%
  • Hypertension
    4%
  • Alanine aminotransferase increased (SGPT > 5X baseline)
    4%
  • Lymphadenopathy
    3%
  • Dyspnea
    3%
  • Malaise
    3%
  • Alopecia
    2%
  • Anxiety
    2%
  • Arthralgia
    2%
  • Constipation
    2%
  • Diarrhea
    2%
  • Dizziness
    2%
  • Dyspepsia
    2%
  • Dysmenorrhea
    2%
  • Leg cramps
    2%
  • Menorrhagia
    2%
  • Myasthenia
    2%
  • Nausea
    2%
  • Nervousness
    2%
  • Palpitations
    2%
  • Peripheral vascular disorder
    2%
  • Prostatic disorder
    2%
  • Tachycardia
    2%
  • Urinary frequency
    2%
  • Vasodilatation
    2%
  • Weight increase
    2%
See more detailed side effects
Risks and risk factors
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings
  • Liver damage
    • Alcohol use
    • Taking drugs that are liver toxic
    • Active or history of liver disease
  • Serious allergic reactions
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Heart problems
    • History of or current heart disease
  • Flu-like symptom complex
  • Harm to fetus
    • Women of childbearing age
  • Injection site reaction
    • Not changing injection sites
  • Blood cell problems
    • Bone marrow suppression
  • Albumin in the product
See more detailed risks and warnings