Compare Aubagio vs. Copaxone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aubagio (Teriflunomide)

Prescription only

Copaxone (Glatiramer)

Prescription only
Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) is an oral medicine that reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. This medication may not be a good choice if you want to get pregnant.

2.5/ 5 average rating with 23 reviewsforAubagio
Lowers the frequency of multiple sclerosis exacerbations.

Copaxone (Glatiramer) is an injectable medicine that's effective for relapsing, remitting MS. It has fewer side effects than other meds, but the self-injections are needed frequently.

3.2/ 5 average rating with 30 reviewsforCopaxone
  • Aubagio (Teriflunomide) lowers relapses, slows disability, and decreases the number of new brain lesions compared to a sugar pill.
  • You can take Aubagio (Teriflunomide) by mouth.
  • Aubagio (Teriflunomide) only needs to be taken once a day, with or without food.
  • One of the main treatments for relapsing multiple sclerosis (MS) that has been around for many years.
  • Helps reduce the frequency of MS relapse episodes.
  • Fewer side effects than other injectable MS medicines, like interferons.
  • Can be helpful in maintaining nerve functions.
  • Likely safe to use during pregnancy.
  • Copaxone (Glatiramer) is a possible treatment for primary-progressive MS (PPMS) even though the clinical evidence is not conclusive (there are currently no approved treatments for PPMS).
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You'll need to have blood tests before and during treatment to make sure you don't have any problems taking Aubagio (Teriflunomide).
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio with an accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or currently take Arava.
  • Requires injections, either day or every other day (but no more than three times a week), depending on the dose you're taking.
  • Injection site reactions are common with pain, redness, swelling, and lipoatrophy (loss of fat under the skin where the injection is made).
  • Doesn't stop the progression of MS.
Used for
Dosage forms
  • Pill
  • Injection
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23 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

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30 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Copaxone (Glatiramer)?

Leave a review
Side effects
9possible side effects
  • Headache
  • Abnormal liver enzymes
  • Diarrhea
  • Hair loss
  • Nausea
  • Burning or prickling sensation in hands, arms, legs, or feet
  • Joint pain
  • Low white blood cells
  • High blood pressure
See more detailed side effects
The Copaxone (Glatiramer) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings
  • Injection reaction
  • Skin damage
  • Chest pain
  • Immunosuppression
  • Risk to fetus
See more detailed risks and warnings