Compare Augmentin vs. amoxicillin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Augmentin
(amoxicillin / clavulanate)

Amoxil
(amoxicillin)

Treats bacterial infections. Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.Treats bacterial infections. Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.
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Coupons for Augmentin
Best available price for 20 (875mg/125mg) tablets of augmentin
Coupons for amoxicillin
Best available price for 30 (500mg) capsules of amoxicillin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.28Augmentin
Reviews for Augmentin
68%
of people (All ages) say Augmentin is worth it
52%
say it works well
13%
say it's a big hassle
1034 reviews
Have you used Augmentin (amoxicillin / clavulanate)?
Worth itNot sureNot worth it
Reviews for amoxicillin
62%
+6% better vs. Augmentin
45%
+7% better vs. Augmentin
14%
+1% better vs. Augmentin
786 reviews
Have you used Amoxil (amoxicillin)?
Worth itNot sureNot worth it
Side effects
Augmentinamoxicillin
  • Diarrhea 9%
  • Nausea 3%
  • Skin rash and hives 3%
More Augmentin side effects »

The amoxicillin FDA package insert doesn’t have numbers about how common side effects are.

More about amoxicillin side effects »
How it works
Augmentinamoxicillin
Augmentin (amoxicillin / clavulanate) contains two antibiotic medicines, which kill bacteria.Amoxil (amoxicillin) is an antibiotic. It kills bacteria, and prevents them from reproducing and making their own protective covering.
Type of medication
Augmentinamoxicillin
Prescription onlyPrescription only
Available as
Augmentinamoxicillin
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
Used for
Augmentinamoxicillin
Risk factors for serious side effects
Augmentinamoxicillin
  • History of penicillin allergies
  • Taking Augmentin (amoxicillin / clavulanate) for a long time
  • Mononucleosis
  • Using oral birth control pills
Detailed Augmentin (amoxicillin / clavulanate) risks & warnings »
  • Taking Amoxil (amoxicillin) for a long time
  • Weakened immune system
  • Not taking Amoxil (amoxicillin) correctly
  • History of penicillin allergies
  • Using oral birth control pills
Detailed Amoxil (amoxicillin) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Food
Augmentinamoxicillin
  • Take with food if you're having upset stomach.
  • Take with food to prevent upset stomach. If you're taking the extended-release version, take within 1 hour of finishing your meal.
Kidneys and liver
Augmentinamoxicillin
  • Liver damage has been associated with patients taking Augmentin (amoxicillin / clavulanate). It's usually reversible, but deaths have been reported. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
No kidneys and liver related info.
Upsides and benefits
Augmentinamoxicillin
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
  • First choice medicine to treat many bacterial infections.
  • Available in generic.
  • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
  • Side effects are generally not too bad compared to other antibiotics.
Downsides and risks
Augmentinamoxicillin
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
  • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
  • Can cause diarrhea, nausea, and vomiting.
  • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
  • The extended-release form can be more expensive because it's a brand name.
Tips from our pharmacists for people taking the medication
Augmentinamoxicillin
  • Finish all of your medicine even if you start to feel better. Stopping it early can cause the infection to come back stronger than before.
  • Can make your oral birth control less effective. Consult your doctor or pharmacist if you need to use backup.
  • Take with food if you're having upset stomach.
  • Store the liquid in the fridge and throw away after 10 days.
  • Shake the suspension thoroughly before using each dose.
  • Finish all of the medicine, even if you start to feel better. Stopping Amoxil (amoxicillin) early can make the infection come back and harder to treat.
  • If you're on birth control, Amoxil (amoxicillin) might make it less effective. Talk to your doctor to see if you need to use backup.
  • Take with food to prevent upset stomach. If you're taking the extended-release version, take within 1 hour of finishing your meal.
  • If you have the liquid, keep the bottle in the fridge. The bottle is only good for 14 days after you pick it up. Shake the bottle well before using each dose.
  • You may have diarrhea or stomach upset when taking Amoxil (amoxicillin), but it should get better soon after you've finished. If the diarrhea gets worse, tell your doctor
Learn more
More about AugmentinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Augmentin (amoxicillin / clavulanate)?
Worth itNot sureNot worth it
More about amoxicillinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Amoxil (amoxicillin)?
Worth itNot sureNot worth it