Compare Augmentin vs. Cleocin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Augmentin
(amoxicillin / clavulanate)

Cleocin T
(clindamycin phosphate)

Treats bacterial infections. Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.28Augmentin
Reviews for Augmentin (amoxicillin / clavulanate)
68%
of people (All ages) say Augmentin (amoxicillin / clavulanate) is worth it
52%
say it works well
13%
say it's a big hassle
1034 reviews
Have you used Augmentin (amoxicillin / clavulanate)?
Worth itNot sureNot worth it
Reviews for Cleocin T (clindamycin phosphate)
57%
-11% worse vs. Augmentin (amoxicillin / clavulanate)
43%
-9% worse vs. Augmentin (amoxicillin / clavulanate)
19%
-6% worse vs. Augmentin (amoxicillin / clavulanate)
115 reviews
Have you used Cleocin T (clindamycin phosphate)?
Worth itNot sureNot worth it
Side effects
AugmentinCleocin
  • Diarrhea 9%
  • Nausea 3%
  • Skin rash and hives 3%
More Augmentin side effects »
  • Any side effect 21%
  • Vaginal moniliasis 8%
  • Vulvovaginitis 6%
  • Vulvovaginal disorder 3%
  • Moniliasis (body) 2%
  • Fungal infection 2%
More Cleocin side effects »
How it works
AugmentinCleocin
Augmentin (amoxicillin / clavulanate) contains two antibiotic medicines, which kill bacteria.Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
AugmentinCleocin
Prescription only
Prescription only
Available as
AugmentinCleocin
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
Used for
AugmentinCleocin
Risk factors for serious side effects
AugmentinCleocin
  • History of penicillin allergies
    • Taking Augmentin (amoxicillin / clavulanate) for a long time
    • Mononucleosis
    • Using oral birth control pills
    Detailed Augmentin (amoxicillin / clavulanate) risks & warnings »
      • History of liver disease
        Detailed Cleocin T (clindamycin phosphate) risks & warnings »
        Pregnancy

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Food
        AugmentinCleocin
        • Take with food if you're having upset stomach.
        • Can be taken with or without food.
        Kidneys and liver
        AugmentinCleocin
        • Liver damage has been associated with patients taking Augmentin (amoxicillin / clavulanate). It's usually reversible, but deaths have been reported. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
        • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
        Pain
        AugmentinCleocin
        No pain related info.
        • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
        Upsides and benefits
        AugmentinCleocin
        • Available as generic product.
        • Available in tablet, capsule, and liquid forms.
        • Used to treat most common types of bacterial infections.
        • Side effects are generally not too bad compared to other antibiotics.
        • Available in generic.
        • Topical form treats acne.
        • Available in different oral forms: tablet, capsule, and suspension.
        • Available in forms to treat skin infections and vaginal infections.
        • Used to treat many types of bacterial infections.
        • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
        • Can be taken with or without food.
        Downsides and risks
        AugmentinCleocin
        • Many bacteria have developed resistance to this antibiotic.
        • Can cause diarrhea, nausea, and vomiting.
        • Birth control pills may not work as well to prevent pregnancy when taking this medication.
        • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
        • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
        • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
        • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
        • If you're taking the topical form, it can cause sensitivity and irritation.
        Tips from our pharmacists for people taking the medication
        AugmentinCleocin
        • Finish all of your medicine even if you start to feel better. Stopping it early can cause the infection to come back stronger than before.
        • Can make your oral birth control less effective. Consult your doctor or pharmacist if you need to use backup.
        • Take with food if you're having upset stomach.
        • Store the liquid in the fridge and throw away after 10 days.
        • Shake the suspension thoroughly before using each dose.
        • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
        • Take this medication exactly how your doctor tells you to.
        • Store the suspension at room temperature.
        • If you're using the topical form, it can take a few weeks to see the full effect.
        • Keep the topical form out of your eyes, nose and mouth.
        • If you're using the topical form, Don't put makeup or bandages over it.
        • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
        Learn more
        More about AugmentinSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Augmentin (amoxicillin / clavulanate)?
        Worth itNot sureNot worth it
        More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Cleocin T (clindamycin phosphate)?
        Worth itNot sureNot worth it