Compare Augmentin vs. Levaquin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Augmentin
(Amoxicillin / Clavulanate)

Levaquin
(Levofloxacin)

Kills bacteria. Augmentin (Amoxicillin / Clavulanate) is good for treating many bacterial infections and is available as generic. However, it will make birth control pills less effective. It also has to be taken with food since it can cause an upset stomach.Kills bacteria. Levaquin (Levofloxacin) is good for treating many bacterial infections and is available as generic. However, it can cause damage to your tendons, and make your skin more sensitive to the sun.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.28Augmentin
Reviews for Augmentin (Amoxicillin / Clavulanate)
68%
of people (All ages) say Augmentin (Amoxicillin / Clavulanate) is worth it
52%
say it works well
13%
say it's a big hassle
1034 reviews
Have you used Augmentin (Amoxicillin / Clavulanate)?
Worth itNot sureNot worth it
Reviews for Levaquin (Levofloxacin)
53%
15% vs. Augmentin (Amoxicillin / Clavulanate)
40%
12% vs. Augmentin (Amoxicillin / Clavulanate)
31%
18% vs. Augmentin (Amoxicillin / Clavulanate)
Have you used Levaquin (Levofloxacin)?
Worth itNot sureNot worth it
Side effects
AugmentinLevaquin

The Augmentin FDA package insert doesn’t have numbers about how common side effects are.

More about Augmentin side effects »

The Levaquin FDA package insert doesn’t have numbers about how common side effects are.

More about Levaquin side effects »
How it works
AugmentinLevaquin
Augmentin (Amoxicillin / Clavulanate) is a combination antibiotic. Amoxicillin kills bacteria and prevents them from reproducing and making their own protective covering. Clavulanate stops chemicals the bacteria make to resist antibiotics.Levaquin (Levofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
AugmentinLevaquin
Antibiotic
Penicillin
Prescription only
Antibiotic
Fluoroquinolone
Prescription only
Available as
AugmentinLevaquin
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
AugmentinLevaquin
Risk factors for serious side effects
AugmentinLevaquin
  • Mononucleosis
  • History of liver disease
Detailed risks & warnings »
  • Over 60 years of age
  • On long-term steroid use
  • Heart, kidney, or lung transplant
  • History of liver disease
  • Seizures
Detailed risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
AugmentinLevaquin
  • Should be taken with food since it can cause stomach upset.
  • Take each dose with a meal since it may cause an upset stomach.
No food related info.
Kidneys and liver
AugmentinLevaquin
  • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
  • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
Pain
AugmentinLevaquin
No pain related info.
  • If you notice pain in your Achilles tendons, contact your doctor.
  • If you notice redness/inflammation, pain or swelling in your joints or muscles, especially in the Achilles tendon, contact your doctor immediately.
  • Talk to your doctor immediately if you start to feel burning, tingling, numbness, pain or you can't tolerate heat or cold. This could be a sign of nerve damage. It can happen as soon as you start taking the medication and may not go away if you stop it.
Upsides and benefits
AugmentinLevaquin
  • Available in generic.
  • Available in different forms: tablet, capsule, and suspension.
  • Used to treat many types of bacterial infections.
  • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Available in generic.
  • Available in different forms: tablet, capsule, and suspension.
  • Used to treat many types of bacterial infections.
  • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
Downsides and risks
AugmentinLevaquin
  • If you're on birth control pills, you should use a barrier method (condoms, diaphragms) since Augmentin can make them less effective.
  • Should be taken with food since it can cause stomach upset.
  • If you have phenylketonuria (PKU), talk to your doctor to prescribe an alternative.
  • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
  • Levofloxacin can make your skin more sensitive to the sun.
  • Can't be used if you've ever had myasthenia gravis.
  • You have to space out any medications with aluminum, magnesium or zinc by at least 2 hours.
  • Can cause changes in taste, headaches, and insomnia.
Tips from our pharmacists for people taking the medication
AugmentinLevaquin
  • Take this medication exactly as your doctor tells you to.
  • Take each dose with a meal since it may cause an upset stomach.
  • If you are taking birth control pills, this can make it less effective.
  • Store the suspension in the refrigerator. All other forms can be kept at room temperature.
  • If you notice pain in your Achilles tendons, contact your doctor.
  • Wear sunscreen if you're going to be out in the sun.
  • Take the medication exactly how the doctor tells you to.
  • Take this medication with plenty of fluids.
  • Space out any medications containing aluminum, magnesium or zinc by at least 2 hours.
  • Can cause diarrhea, nausea or vomiting.
  • Can cause changes in taste, headaches and insomnia.
Learn more
More about AugmentinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Augmentin (Amoxicillin / Clavulanate)?
Worth itNot sureNot worth it
More about LevaquinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Levaquin (Levofloxacin)?
Worth itNot sureNot worth it