Compare Augmentin vs. Levaquin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Augmentin
(Amoxicillin / Clavulanate)

Levaquin
(Levofloxacin)

Kills bacteria. Augmentin (Amoxicillin / Clavulanate) is good for treating many bacterial infections and is available as generic. However, it will make birth control pills less effective. It also has to be taken with food since it can cause an upset stomach.Kills bacteria. Levaquin (Levofloxacin) is good for treating many bacterial infections and is available as generic. However, it can cause damage to your tendons, and make your skin more sensitive to the sun.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.293137254901961Augmentin
Reviews for Augmentin (Amoxicillin / Clavulanate)
68%
of people say Augmentin (Amoxicillin / Clavulanate) is worth it
52%
say it works well
13%
say it's a big hassle
Reviews for Levaquin (Levofloxacin)
54%
14% vs. Augmentin (Amoxicillin / Clavulanate)
39%
13% vs. Augmentin (Amoxicillin / Clavulanate)
29%
16% vs. Augmentin (Amoxicillin / Clavulanate)
Side effects
AugmentinLevaquin

The Augmentin FDA package insert doesn’t have numbers about how common side effects are.

More about Augmentin side effects »

The Levaquin FDA package insert doesn’t have numbers about how common side effects are.

More about Levaquin side effects »
How it works
AugmentinLevaquin
Augmentin (Amoxicillin / Clavulanate) is a combination antibiotic. Amoxicillin kills bacteria and prevents them from reproducing and making their own protective covering. Clavulanate stops chemicals the bacteria make to resist antibiotics.Levaquin (Levofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
AugmentinLevaquin
Antibiotic
Penicillin
Prescription only
Antibiotic
Fluoroquinolone
Prescription only
Available as
AugmentinLevaquin
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
AugmentinLevaquin
Risk factors for serious side effects
AugmentinLevaquin
  • Mononucleosis
    • History of liver disease
      Detailed Augmentin (Amoxicillin / Clavulanate) risks & warnings »
      • Over 60 years of age
      • On long-term steroid use
      • Heart, kidney, or lung transplant
        • History of liver disease
        • Seizures
            • Diabetes
            • Taking medications for diabetes
                Detailed Levaquin (Levofloxacin) risks & warnings »
                Pregnancy category
                AugmentinLevaquin
                BFDA pregnancy category (Probably safe)

                Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

                See the FDA package insert
                CFDA pregnancy category (Weigh risks vs. benefits)

                Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                See the FDA package insert
                Alcohol
                No specific alcohol-related info.No specific alcohol-related info.
                Food
                • Should be taken with food since it can cause stomach upset.
                • Take each dose with a meal since it may cause an upset stomach.
                No specific food-related info.
                Kidneys and liver
                No specific kidneys and liver-related info.No specific kidneys and liver-related info.
                Sex
                No specific sex-related info.No specific sex-related info.
                Sleep
                No specific sleep-related info.No specific sleep-related info.
                Weight
                No specific weight-related info.No specific weight-related info.
                Upsides and benefits
                AugmentinLevaquin
                • Available in generic.
                • Available in different forms: tablet, capsule, and suspension.
                • Used to treat many types of bacterial infections.
                • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
                • Available in generic.
                • Available in different forms: tablet, capsule, and suspension.
                • Used to treat many types of bacterial infections.
                • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
                Downsides and risks
                AugmentinLevaquin
                • If you're on birth control pills, you should use a barrier method (condoms, diaphragms) since Augmentin can make them less effective.
                • Should be taken with food since it can cause stomach upset.
                • If you have phenylketonuria (PKU), talk to your doctor to prescribe an alternative.
                • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
                • Levofloxacin can make your skin more sensitive to the sun.
                • Can't be used if you've ever had myasthenia gravis.
                • You have to space out any medications with aluminum, magnesium or zinc by at least 2 hours.
                • Can cause changes in taste, headaches, and insomnia.
                Tips from our pharmacists for people taking the medication
                AugmentinLevaquin
                • Take this medication exactly as your doctor tells you to.
                • Take each dose with a meal since it may cause an upset stomach.
                • If you are taking birth control pills, this can make it less effective.
                • Store the suspension in the refrigerator. All other forms can be kept at room temperature.
                • If you notice pain in your Achilles tendons, contact your doctor.
                • Wear sunscreen if you're going to be out in the sun.
                • Take the medication exactly how the doctor tells you to.
                • Take this medication with plenty of fluids.
                • Space out any medications containing aluminum, magnesium or zinc by at least 2 hours.
                • Can cause diarrhea, nausea or vomiting.
                • Can cause changes in taste, headaches and insomnia.
                Learn more
                More about AugmentinSide effectsReviews & ratingsAlternativesFDA package insert
                More about LevaquinSide effectsReviews & ratingsAlternativesFDA package insert