Compare Augmentin vs. Levaquin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Augmentin
(amoxicillin / clavulanate)

Levaquin
(levofloxacin)

Treats bacterial infections. Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.Kills bacteria. Levaquin (Levofloxacin) is good for treating many bacterial infections and is available as generic. However, it can cause damage to your tendons, and make your skin more sensitive to the sun.
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Coupons for Levaquin
Best available price for 10 (500mg) tablets of levofloxacin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.28Augmentin
Reviews for Augmentin (amoxicillin / clavulanate)
68%
of people (All ages) say Augmentin (amoxicillin / clavulanate) is worth it
52%
say it works well
13%
say it's a big hassle
1034 reviews
Have you used Augmentin (amoxicillin / clavulanate)?
Worth itNot sureNot worth it
Reviews for Levaquin (levofloxacin)
53%
-15% worse vs. Augmentin (amoxicillin / clavulanate)
40%
-12% worse vs. Augmentin (amoxicillin / clavulanate)
31%
-18% worse vs. Augmentin (amoxicillin / clavulanate)
Have you used Levaquin (levofloxacin)?
Worth itNot sureNot worth it
Side effects
AugmentinLevaquin
  • Diarrhea 9%
  • Nausea 3%
  • Skin rash and hives 3%
More Augmentin side effects »
  • Nausea 7%
  • Headache 6%
  • Diarrhea 5%
  • Sleep difficulty 4%
  • Dizziness 3%
  • Consitpation 3%
  • Abdominal pain 2%
  • Vomiting 2%
  • Indigestion 2%
  • Rash 2%
More Levaquin side effects »
How it works
AugmentinLevaquin
Augmentin (amoxicillin / clavulanate) contains two antibiotic medicines, which kill bacteria.Levaquin (Levofloxacin) is an antibiotic. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
AugmentinLevaquin
Prescription only
Prescription only
Available as
AugmentinLevaquin
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Pill
  • Liquid
Used for
AugmentinLevaquin
Risk factors for serious side effects
AugmentinLevaquin
  • History of penicillin allergies
  • Taking Augmentin (amoxicillin / clavulanate) for a long time
  • Mononucleosis
  • Using oral birth control pills
Detailed Augmentin (amoxicillin / clavulanate) risks & warnings »
  • Over 60 years of age
  • On long-term steroid use
  • Heart, kidney, or lung transplant
  • History of liver disease
  • Seizures
Detailed Levaquin (levofloxacin) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
AugmentinLevaquin
  • Take with food if you're having upset stomach.
No food related info.
Kidneys and liver
AugmentinLevaquin
  • Liver damage has been associated with patients taking Augmentin (amoxicillin / clavulanate). It's usually reversible, but deaths have been reported. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
  • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
Pain
AugmentinLevaquin
No pain related info.
  • If you notice pain in your Achilles tendons, contact your doctor.
  • If you notice redness/inflammation, pain or swelling in your joints or muscles, especially in the Achilles tendon, contact your doctor immediately.
  • Talk to your doctor immediately if you start to feel burning, tingling, numbness, pain or you can't tolerate heat or cold. This could be a sign of nerve damage. It can happen as soon as you start taking the medication and may not go away if you stop it.
Upsides and benefits
AugmentinLevaquin
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
  • Available in generic.
  • Available in different forms: tablet, capsule, and suspension.
  • Used to treat many types of bacterial infections.
  • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
Downsides and risks
AugmentinLevaquin
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
  • Must be used with caution in people over 60 years of age, or who have had either an organ transplant or on long-term steroid use due to possible tendon rupture.
  • Levofloxacin can make your skin more sensitive to the sun.
  • Can't be used if you've ever had myasthenia gravis.
  • You have to space out any medications with aluminum, magnesium or zinc by at least 2 hours.
  • Can cause changes in taste, headaches, and insomnia.
Tips from our pharmacists for people taking the medication
AugmentinLevaquin
  • Finish all of your medicine even if you start to feel better. Stopping it early can cause the infection to come back stronger than before.
  • Can make your oral birth control less effective. Consult your doctor or pharmacist if you need to use backup.
  • Take with food if you're having upset stomach.
  • Store the liquid in the fridge and throw away after 10 days.
  • Shake the suspension thoroughly before using each dose.
  • If you notice pain in your Achilles tendons, contact your doctor.
  • Wear sunscreen if you're going to be out in the sun.
  • Take the medication exactly how the doctor tells you to.
  • Take this medication with plenty of fluids.
  • Space out any medications containing aluminum, magnesium or zinc by at least 2 hours.
  • Can cause diarrhea, nausea or vomiting.
  • Can cause changes in taste, headaches and insomnia.
Learn more
More about AugmentinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Augmentin (amoxicillin / clavulanate)?
Worth itNot sureNot worth it
More about LevaquinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Levaquin (levofloxacin)?
Worth itNot sureNot worth it