Compare Avapro vs. Benicar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Avapro
(irbesartan)

Benicar
(olmesartan)

Lowers blood pressure. Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.Lowers blood pressure. Benicar (olmesartan) is a good blood pressure-lowering medicine that protects your kidneys, but with fewer side effects.
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Coupons for Avapro
Best available price for 30 (300mg) tablets of irbesartan
Coupons for Benicar
Best available price for 30 (20mg) tablets of benicar
Reviews & ratings
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Have you used Avapro (irbesartan)?
Worth itNot sureNot worth it
Reviews for Benicar
65%
+35% better vs. Avapro
63%
+12% better vs. Avapro
12%
+12% better vs. Avapro
118 reviews
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it
Side effects
AvaproBenicar
  • Fatigue 1%
  • Diarrhea 1%
  • Heartburn 1%
More Avapro side effects »
  • Dizziness 2%
More Benicar side effects »
How it works
AvaproBenicar
Avapro (irbesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.Benicar (olmesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.
Type of medication
AvaproBenicar
Prescription onlyPrescription only
Available as
AvaproBenicar
  • Pill
  • Pill
Used for
AvaproBenicar
Risk factors for serious side effects
AvaproBenicar
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Avapro (irbesartan) risks & warnings »
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Benicar (olmesartan) risks & warnings »
Pregnancy
Kidneys and liver
AvaproBenicar
  • Avapro (irbesartan) can hurt your kidneys. If you already have kidney damage, Avapro (irbesartan) could make it worse. Your doctor will do regular blood tests to check your kidneys, usually before you start Avapro (irbesartan), and at least once a year while you're still on it.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Benicar (olmesartan) can hurt your kidneys. If you already have some degree of kidney damage, Benicar (olmesartan) could make it worse. It's important to get blood work done to check your kidney function before starting Benicar (olmesartan) and at least once a year while you're still taking it.
  • Requires regular blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Weight
AvaproBenicar
No weight related info.
  • Benicar (olmesartan) has been reported to cause severe diarrhea and weight loss unexplained by other causes. Stay hydrated and notify your doctor if you continue to have more than 3-4 loose stools a day.
Upsides and benefits
AvaproBenicar
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Available by itself and in combination with different blood pressure medicines in a single pill.
Downsides and risks
AvaproBenicar
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
  • Requires regular blood tests to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Recently became a generic, though still relatively expensive.
Tips from our pharmacists for people taking the medication
AvaproBenicar
  • Avapro (irbesartan) can make you feel a little dizzy for the first few days.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Don't eat a lot of foods that are high in potassium or use salt substitutes that contain potassium.
  • Tell your doctor about any dizziness or muscle weakness that doesn't go away after the first few days.
  • Don't take Avapro (irbesartan) if you're pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires regular blood tests to check kidney function.
  • Don't take it if you're pregnant.
Learn more
More about AvaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Avapro (irbesartan)?
Worth itNot sureNot worth it
More about BenicarSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it