Compare Avonex vs. Aubagio

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aubagio (Teriflunomide)

Prescription only
Lowers the frequency of multiple sclerosis exacerbations.

Avonex (Interferon Beta-1A) is an injectable medicine effective for relapsing, remitting MS and has manageable side effects and weekly dosing.

2.7/ 5 average rating with 33 reviewsforAvonex
Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) is an oral medicine that reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. This medication may not be a good choice if you want to get pregnant.

2.5/ 5 average rating with 23 reviewsforAubagio
Upsides
  • One of the main treatments for relapsing MS that has been around for many years.
  • Injections are given weekly, and not daily like other MS medications.
  • Helps reduce the frequency of MS relapse episodes.
  • Flu-like reactions are the most common side effects and usually go away with continued treatment or can be avoided by using over-the-counter pain and fever-reducing medicines before the injection (like acetaminophen or ibuprofen).
  • Aubagio (Teriflunomide) lowers relapses, slows disability, and decreases the number of new brain lesions compared to a sugar pill.
  • You can take Aubagio (Teriflunomide) by mouth.
  • Aubagio (Teriflunomide) only needs to be taken once a day, with or without food.
Downsides
  • Injection site reactions are common, ranging from localized pain, redness, and swelling to severe skin dryness.
  • Flu-like symptoms are common after interferon injections.
  • It's not clear what type of problems occur if taken during pregnancy.
  • Blood testing is required before and during use of Avonex (Interferon Beta-1A).
  • May not be as effective as other interferons.
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You'll need to have blood tests before and during treatment to make sure you don't have any problems taking Aubagio (Teriflunomide).
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio with an accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or currently take Arava.
Used for
Dosage forms
  • Injection
  • Pill
Price
Lowest price
$7018.93
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Lowest price
$17360.20
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Reviews
33 reviews so far
36%
saidit'sworth it
24%
saiditworked well
33%
saidit'sa big hassle

Have you used Avonex (Interferon Beta-1A)?

Leave a review
23 reviews so far
43%
saidit'sworth it
26%
saiditworked well
30%
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
Side effects
29possible side effects
  • Headache
    57%
  • Flu-like symptoms
    49%
  • Myalgia
    28%
  • Asthenia
    24%
  • Pain
    23%
  • Nausea
    23%
  • Fever
    20%
  • Chills
    19%
  • Depression
    18%
  • Urinary tract infection
    17%
  • Dizziness
    14%
  • Upper respiratory tract infection
    14%
  • Sinusitis
    14%
  • Arthralgia
    9%
  • Abdominal pain
    8%
  • Injection site pain
    8%
  • Bronchitis
    8%
  • Infection
    7%
  • Injuction site inflammation
    6%
  • Injection site ecchymosis
    6%
  • Chest pain
    5%
  • Migraine
    5%
  • Alopecia
    4%
  • Eye disorder
    4%
  • Anemia
    4%
  • Injection site reaction
    3%
  • Toothache
    3%
  • Urine constituents abnormal
    3%
  • Vasodilation
    2%
See more detailed side effects
9possible side effects
  • Headache
    18%
  • Abnormal liver enzymes
    13%
  • Diarrhea
    13%
  • Hair loss
    10%
  • Nausea
    8%
  • Burning or prickling sensation in hands, arms, legs, or feet
    8%
  • Joint pain
    8%
  • Low white blood cells
    4%
  • High blood pressure
    3%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Serious allergic reaction
    • Allergy to albumin
    • Prolonged use of Avonex (Interferon Beta-1A)
  • Liver damage
    • Alcohol use
    • Taking drugs that are liver toxic
    • History of liver disease
  • Injection site reaction
  • Heart problems
    • History of heart disease
  • Immune reactions
  • Albumin in the product
  • Seizures
    • History of seizures
  • Risk to fetus
    • Women of childbearing age
  • Bone marrow suppression
See more detailed risks and warnings
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings