Compare Axert vs. Onzetra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Axert
(almotriptan)

Onzetra
(sumatriptan)

Coming soon.Treats migraine headaches. Onzetra (sumatriptan) is the only medicine that's available in a breath-powered nose powder to treat migraines. However, it can be expensive compared to other medicines.
Reviews & ratings
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Have you used Axert (almotriptan)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Onzetra (sumatriptan)?
Worth itNot sureNot worth it
Side effects
AxertOnzetra

We haven’t found good data for Axert side effects.

FDA side effect reports for Axert »
  • Changes in taste 17%
  • Discomfort in the nose 10%
  • Runny nose 3%
  • Stuffy nose 2%
More Onzetra side effects »
How it works
AxertOnzetra
Coming soon.Onzetra (sumatriptan) is a selective serotonin receptor agonist called a triptan. It's believed that migraine headaches happen when blood vessels are too open and allow too much blood in the brain. Onzetra (sumatriptan) tightens the blood vessels, which relieves the pain.
Type of medication
AxertOnzetra
Prescription only
Available as
AxertOnzetra
  • Pill
  • Nasal powder
Used for
AxertOnzetra
  • Migraine Acute
Risk factors for serious side effects
AxertOnzetra
    Coming soon.
    • Heart disease
    • History of chest pain
    • Uncontrolled high blood pressure
    • History of a stroke
    • Using Onzetra (sumatriptan) for more than 10 days a month
    Detailed Onzetra (sumatriptan) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    AxertOnzetra
    Coming soon
    • Compared to pills, Onzetra (sumatriptan) is better absorbed in the body and good if it's hard to take pills.
    • Onzetra (sumatriptan) is a first choice medicine to treat migraines.
    • There is a copay program available that can make Onzetra (sumatriptan) cheaper.
    Downsides and risks
    AxertOnzetra
    Coming soon
    • It can be very expensive. There are other forms of this same medicine that are much cheaper, including a nose spray.
    • You have to use two nosepieces to get the full dose of Onzetra (sumatriptan), which can be hard to remember.
    • Onzetra (sumatriptan) is only available in one strength.
    Tips from our pharmacists for people taking the medication
    AxertOnzetra
    Coming soon
    • Follow the instructions exactly as shown by the package insert and your doctor or pharmacist; otherwise, Onzetra (sumatriptan) won't work correctly and you won't get any medicine.
    • Onzetra (sumatriptan) can only treat a migraine that's already happening. You can't use it to stop migraines from starting.
    • You have to use 2 nosepieces of Onzetra (sumatriptan) to get the full dose of medicine.
    • Don't use more than 2 full doses (4 nosepieces) in a 24-hour period.
    • If you're using more than 8 doses of Onzetra (sumatriptan) a month, talk to your doctor to see if you should try another medicine.
    • You can only use each nosepiece of Onzetra (sumatriptan) once. Throw it away in the trash after you've checked that you used the medicine correctly.
    Learn more
    More about AxertSide effectsReviews & ratingsFDA package insert
    Have you used Axert (almotriptan)?
    Worth itNot sureNot worth it
    More about OnzetraSide effectsAlternativesFDA package insert
    Have you used Onzetra (sumatriptan)?
    Worth itNot sureNot worth it