Compare Axert vs. Onzetra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

No information currently available
Treats migraine headaches.

Onzetra (sumatriptan) is the only medicine that's available in a breath-powered nose powder to treat migraines. However, it can be expensive compared to other medicines.

Upsides
No information currently available
  • Compared to pills, Onzetra (sumatriptan) is better absorbed in the body and good if it's hard to take pills.
  • Onzetra (sumatriptan) is a first choice medicine to treat migraines.
  • There is a copay program available that can make Onzetra (sumatriptan) cheaper.
Downsides
No information currently available
  • It can be very expensive. There are other forms of this same medicine that are much cheaper, including a nose spray.
  • You have to use two nosepieces to get the full dose of Onzetra (sumatriptan), which can be hard to remember.
  • Onzetra (sumatriptan) is only available in one strength.
Used for
  • Migraine (Acute)
Dosage forms
  • Pill
  • Nasal powder
Price
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Reviews
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Side effects
The Axert (Almotriptan) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Changes in taste
    20%
  • Discomfort in the nose
    11%
  • Runny nose
    5%
  • Stuffy nose
    2%
See more detailed side effects
Risks and risk factors
No information currently available
  • Heart attack
    • Heart disease
    • History of chest pain
    • Uncontrolled high blood pressure
  • Stroke
    • History of a stroke
  • Medication overuse headache
    • Using Onzetra (sumatriptan) for more than 10 days a month
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Higher blood pressure
    • Uncontrolled high blood pressure
  • Suicidal behavior
    • Taking medicines for seizures
  • Blood vessel issues
    • High blood pressure
    • History of stroke
See more detailed risks and warnings