Compare Axiron vs. Testim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Axiron
(Testosterone Topical Solution)

Testim
(Testosterone Gel)

Treats low testosterone. This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.Treats low testosterone. This testosterone gel comes in convenient daily doses, but you have to be careful about skin-to-skin contact with other people.
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Reviews & ratings
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Side effects
AxironTestim

The Axiron FDA package insert doesn’t have numbers about how common side effects are.

More about Axiron side effects »
  • Application site reactions 1%
  • Increase in hemoglobin (≥ 19 g/dl) 1%
  • Increase in hematocrit (≥ 58%) 1%
More Testim side effects »
How it works
AxironTestim
Testosterone topical solution works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.Testosterone gel works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
AxironTestim
Hormone replacement
Testosterone
Prescription only
Hormone replacement
Testosterone
Prescription only
Available as
AxironTestim
  • Topical
  • Cream, gel, or ointment
Used for (click to learn more)
AxironTestim
  • Low testosterone
  • Low testosterone
Risk factors for serious side effects
AxironTestim
Coming soon.Coming soon.
Pregnancy category
AxironTestim
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
AxironTestim
  • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
  • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
  • You apply it to your shoulders and upper arms like a lotion, so it's easy to use.
  • Available in individual daily doses, so it's more convenient than some alternatives.
Downsides and risks
AxironTestim
  • Only available as brand name.
  • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
  • Not available in generic form, so it can be more expensive.
  • You have to let the skin dry after you've put on testosterone gel, and you have to wear clothes over the area to prevent the medication from spreading onto other people.
  • You have to wait at least 2 hours after applying testosterone gel before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
Tips from our pharmacists for people taking the medication
AxironTestim
  • Prime testosterone topical solution first by pumping 3 times before you use a new bottle.
  • If you use deodorant or antiperspirant, apply that first before using testosterone topical solution.
  • Don't swim or bathe for at least 2 hours after you put on testosterone topical solution so that it has time to absorb.
  • Cover the area with clothing as soon as it's dry so you don't spread it to other people.
  • If you think you'll have skin-to-skin contact at the area where you've placed testosterone topical solution, wash that area with soap and water then dry.
  • Don't use testosterone topical solution anywhere besides your armpits.
  • Use the entire contents of one tube each day and apply to your shoulders and upper arms. Don't put it anywhere else.
  • Don't swim or bathe for at least 2 hours after you apply testosterone gel.
  • Cover the area with clothing as soon as it's dry so you don't spread it to other people, and wash your hands with soap and water.
  • If you think you'll have skin-to-skin contact at the area where you've placed testosterone gel, wash that area with soap and water then dry.
Learn more
More about AxironSide effectsReviews & ratingsAlternativesFDA package insert
More about TestimSide effectsReviews & ratingsAlternativesFDA package insert