Compare Axiron vs. Testim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.

Treats low testosterone.

This testosterone gel comes in convenient daily doses, but you have to be careful about skin-to-skin contact with other people.

Upsides
  • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
  • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
  • You apply it to your shoulders and upper arms like a lotion, so it's easy to use.
  • Available in individual daily doses, so it's more convenient than some alternatives.
Downsides
  • Only available as brand name.
  • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
  • Not available in generic form, so it can be more expensive.
  • You have to let the skin dry after you've put on testosterone gel, and you have to wear clothes over the area to prevent the medication from spreading onto other people.
  • You have to wait at least 2 hours after applying testosterone gel before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
Used for
  • Low testosterone
  • Low testosterone
Dosage forms
  • Topical
  • Cream, gel, or ointment
Price
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Reviews
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Side effects
7possible side effects
  • Application Site Irritation
    8%
  • Application Site Erythema
    7%
  • Hematocrit Increased
    7%
  • Headache
    6%
  • Diarrhea
    4%
  • Vomiting
    4%
  • PSA Increased
    4%
See more detailed side effects
The Testim (Testosterone Gel) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
No information currently available
No information currently available