Compare azithromycin vs. Augmentin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats bacterial infections.

Zithromax (azithromycin) is good for treating many bacterial infections and is available in generic form. However, it may cause headache, dizziness, or rash.

4.0/ 5 average rating with 909 reviewsforazithromycin
Treats bacterial infections.

Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.

3.9/ 5 average rating with 1034 reviewsforAugmentin
Upsides
  • Available as a generic in the tablet and suspension form.
  • The suspension can be used if you have problems swallowing.
  • Used to treat many types of bacterial infections.
  • Bacteria is less resistant to this antibiotic, meaning that Zithromax (azithromycin) will fight off the bacteria better. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Immediate release form can be taken with or without food.
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
Downsides
  • Must space out antacids by at least 2 hours.
  • Use with caution if you have liver disease.
  • Must be used with caution if you are on medications to thin the blood (anticoagulants) because of increased risk of bleeding.
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
Used for
Dosage forms
  • Pill
  • Liquid
  • Extended-release liquid
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
Price
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Reviews
909 reviews so far
74%
saidit'sworth it
59%
saiditworked well
11%
saidit'sa big hassle

Have you used Zithromax (azithromycin)?

Leave a review
1034 reviews so far
68%
saidit'sworth it
52%
saiditworked well
13%
saidit'sa big hassle

Have you used Augmentin (amoxicillin / clavulanate)?

Leave a review
Side effects
3possible side effects
  • Vomiting
    5%
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
3possible side effects
  • Diarrhea
    15%
  • Vaginal yeast infection
    3%
  • Nausea
    2%
See more detailed side effects
Risks and risk factors
  • Diarrhea caused by bacteria (Clostridium difficile)
  • Liver damage
    • History of liver disease
  • Myasthenia gravis
    • Myasthenia gravis
  • Serious allergic reaction
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
    • Elderly
See more detailed risks and warnings
  • Serious allergic reaction
    • History of penicillin allergy
    • History of multiple allergies
  • Liver damage
    • Existing liver problems
    • Taking other medicines that harm the liver
  • Superinfection
    • Taking Augmentin (amoxicillin / clavulanate) for a long time
    • Older age
    • Taking immunosuppressant medicines
  • Rash
    • Mononucleosis
See more detailed risks and warnings