Compare azithromycin vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zithromax (azithromycin)

Prescription only
Treats bacterial infections.

Zithromax (azithromycin) is good for treating many bacterial infections and is available in generic form. However, it may cause headache, dizziness, or rash.

5.5/ 7 average rating with 909 reviewsforazithromycin
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

5.0/ 7 average rating with 473 reviewsforBactrim
Upsides
  • Available as a generic in the tablet and suspension form.
  • The suspension can be used if you have problems swallowing.
  • Used to treat many types of bacterial infections.
  • Bacteria is less resistant to this antibiotic, meaning that Zithromax (azithromycin) will fight off the bacteria better. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Immediate release form can be taken with or without food.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • Must space out antacids by at least 2 hours.
  • Use with caution if you have liver disease.
  • Must be used with caution if you are on medications to thin the blood (anticoagulants) because of increased risk of bleeding.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
Used for
Dosage forms
  • Pill
  • Liquid
  • Extended-release liquid
  • Pill
  • Liquid
Price
Lowest price near you
$9.89
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$4
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Reviews
909 
74%
think this treatment is worth it
59%
think this treatment works well
11%
think this treatment is a hassle

Have you used Zithromax (azithromycin)?

Leave a review
473 
59%
think this treatment is worth it
49%
think this treatment works well
22%
think this treatment is a hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
3possible side effects
  • Vomiting
    5%
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Liver damage

    History of liver disease

  • Myasthenia gravis

    Myasthenia gravis

  • Abnormal heartbeat

    QT prolongation

    ...and 4 more risk factors

See more detailed risks and warnings
  • Lower kidney function

    Elderly

    ...and 1 more risk factors

See more detailed risks and warnings