Compare azithromycin vs. Benzamycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats bacterial infections.

Zithromax (azithromycin) is good for treating many bacterial infections and is available in generic form. However, it may cause headache, dizziness, or rash.

4.0/ 5 average rating with 909 reviewsforazithromycin
Topical treatment for acne.

Benzamycin (Benzoyl Peroxide / Erythromycin) is a topical combination acne treatment that may work better for people who didn't see an improvement when taking either medicine alone or simply don't want to take pill medication. You need to be careful because it can bleach your hair, clothing and other fabrics. It also needs to be stored in the refrigerator and is only good for three months..

3.4/ 5 average rating with 146 reviewsforBenzamycin
Upsides
  • Available as a generic in the tablet and suspension form.
  • The suspension can be used if you have problems swallowing.
  • Used to treat many types of bacterial infections.
  • Bacteria is less resistant to this antibiotic, meaning that Zithromax (azithromycin) will fight off the bacteria better. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Immediate release form can be taken with or without food.
  • Benzamycin works better to reduce bacteria in oil glands and improve overall signs and symptoms of acne than either medicine alone.
  • Reduces bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
  • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin not working as well over time.
  • Although Benzamycin can irritate the skin, a true skin allergy is rare.
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
Downsides
  • Must space out antacids by at least 2 hours.
  • Use with caution if you have liver disease.
  • Must be used with caution if you are on medications to thin the blood (anticoagulants) because of increased risk of bleeding.
  • There's a risk of irritation with anything you apply to your skin and this is no different. Benzamycin, contains a topical antibiotic and can cause redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis).
  • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
  • Can cause bleaching of hair and clothing.
  • You'll need to stay out of the sun or apply a sunscreen if you go outdoors.
Used for
Dosage forms
  • Pill
  • Liquid
  • Extended-release liquid
  • Cream, gel, or ointment
Price
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Reviews
909 reviews so far
74%
saidit'sworth it
59%
saiditworked well
11%
saidit'sa big hassle

Have you used Zithromax (azithromycin)?

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146 reviews so far
54%
saidit'sworth it
26%
saiditworked well
12%
saidit'sa big hassle

Have you used Benzamycin (Benzoyl Peroxide / Erythromycin)?

Leave a review
Side effects
3possible side effects
  • Vomiting
    5%
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
2possible side effects
  • Dyness
    3%
  • Urticarial reaction
    3%
See more detailed side effects
Risks and risk factors
  • Diarrhea caused by bacteria (Clostridium difficile)
  • Liver damage
    • History of liver disease
  • Myasthenia gravis
    • Myasthenia gravis
  • Serious allergic reaction
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
    • Elderly
See more detailed risks and warnings
  • Bleaching effects
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Allergic reaction
  • Development of more serious infections
    • Long-term use of Benzamycin (Benzoyl Peroxide / Erythromycin)
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.