Compare baclofen vs. Myrbetriq

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lioresal (baclofen)

Prescription only

Myrbetriq (mirabegron)

Prescription only
Relaxes your muscles.

Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.

3.5/ 5 average rating with 33 reviewsforbaclofen
Treats overactive bladder.

Myrbetriq (mirabegron) is a good treatment for overactive bladder with the least chance for dry mouth and constipation, but talk to your doctor if you have high blood pressure.

Upsides
  • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
  • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
  • Myrbetriq (mirabegron) helps you to have better control over your urination.
  • Myrbetriq (mirabegron) causes less drowsiness and constipation than other medicines for overactive bladder.
  • May be used if you have glaucoma.
  • Myrbetriq (mirabegron) may be safer to use if you are over 65 years old.
Downsides
  • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
  • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
  • Lioresal (baclofen) can make you sleepy.
  • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
  • Myrbetriq (mirabegron) might raise your blood pressure.
  • If you have an obstruction in your bladder, Myrbetriq (mirabegron) might make you retain more urine.
  • Myrbetriq (mirabegron) may be very expensive depending on your insurance.
  • Not recommended if you have severe liver or kidney disease.
Used for
Dosage forms
  • Pill
  • Extended release
Price
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Reviews
33 reviews so far
61%
saidit'sworth it
55%
saiditworked well
15%
saidit'sa big hassle

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Side effects
1possible side effects
  • Drowsiness
    63%
See more detailed side effects
8possible side effects
  • High blood pressure
    11%
  • Common cold symptoms
    4%
  • Urinary tract infection
    4%
  • Headache
    2%
  • Constipation
    2%
  • Chest cold infection
    2%
  • Joint pain
    2%
  • Rapid heart beat
    2%
See more detailed side effects
Risks and risk factors
  • Withdrawal symptoms
    • Stopping Lioresal (baclofen) too quickly
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
  • Seizures
    • Higher dose
    • Using other medicines that can cause seizures
    • History of seizures
    • Alcoholism
    • Eating disorders
    • Brain infections
See more detailed risks and warnings
  • Increased blood pressure
    • Untreated high blood pressure
  • Urinary retention
    • Bladder outlet obstruction
  • Unusual swelling
See more detailed risks and warnings