Compare Baclofen vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lioresal
(baclofen)

Soma
(carisoprodol)

Relaxes your muscles. Lioresal (Baclofen) is effective for long term spastic conditions, such as multiple sclerosis, spinal cord injury, and others.Relaxes your muscles. Soma (Carisoprodol) is widely used to treat muscle spasms and is available as a generic, but it's not considered a first-choice treatment for muscle spasms. It's also not meant for long-term therapy.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for
Prices and coupon for 90 (10mg) tablets of baclofen
Coupons for
Prices and coupon for 90 (350mg) tablets of carisoprodol
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.79Baclofen
Reviews for Lioresal (baclofen)
61%
of people (All ages) say Lioresal (baclofen) is worth it
55%
say it works well
15%
say it's a big hassle
Have you used Lioresal (baclofen)?
Worth itNot sureNot worth it
Reviews for Soma (carisoprodol)
61%
Same vs. Lioresal (baclofen)
39%
-16% worse vs. Lioresal (baclofen)
9%
+6% better vs. Lioresal (baclofen)
220 reviews
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it
Side effects
BaclofenSoma

We haven’t found good data for Baclofen side effects.

FDA side effect reports for Baclofen »
  • Drowsiness 7%
  • Dizziness 6%
  • Hedache 3%
  • Central nervous system reactions 2%
More Soma side effects »
How it works
BaclofenSoma
Lioresal (Baclofen) is a muscle relaxer. It works in the nervous system to calm down muscle spasms without interfering with normal muscle function.Soma (Carisoprodol) is a muscle relaxant. It works in the brain to help calm down muscle spasms.
Type of medication
BaclofenSoma
Prescription only
Prescription only
Available as
BaclofenSoma
  • Pill
  • Dissolving tablet
  • Pill
Used for
BaclofenSoma
Risk factors for serious side effects
BaclofenSoma
  • Stopping Lioresal (Baclofen) too quickly
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
  • Higher dose
  • Using other medicines that can cause seizures
  • History of seizures
  • Alcoholism
  • Eating disorders
  • Brain infections
Detailed Lioresal (baclofen) risks & warnings »
  • Taking other medications that also cause sleepiness
  • Recreational drug use
  • Excessive alcohol use
  • Prior history of drug abuse
  • Prior history of overdoses of drugs of abuse, recreational drugs or alcohol
Detailed Soma (carisoprodol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
BaclofenSoma
  • Don't drink alcohol while using this.
  • Don't drink alcohol while on this medication.
Pain
BaclofenSoma
  • Relieves pain associated with muscle spasms.
  • Can cause stomach pain, nausea and vomiting.
Sleep
BaclofenSoma
  • Can cause extreme drowsiness or dizziness if you're taking it with high blood pressure medications.
No sleep related info.
Upsides and benefits
BaclofenSoma
  • Lioresal (Baclofen) is effective for treating muscle spasms, as well as being an effective muscle relaxant.
  • Can be used long term.
  • Relieves pain associated with muscle spasms.
  • A better option for seniors compared to other muscle relaxants since it has less side effects than the other meds.
  • Lioresal (Baclofen) is available as a generic and is a relatively inexpensive medication.
  • Available in generic.
  • Available in two different strengths, although the smaller strength is only available as brand name and thus more expensive.
Downsides and risks
BaclofenSoma
  • If taking regularly, you shouldn't stop taking Lioresal (Baclofen) abruptly. You'll need to get off of it slowly.
  • Be careful if taking other drugs that affect your ability to stay awake, since Lioresal (Baclofen) can make you much more tired.
  • Not first line for treating muscle spasms.
  • Can cause dizziness and sleepiness.
  • Not meant for long term therapy.
  • Can cause dependence and withdrawal symptoms if you stop taking it suddenly.
Tips from our pharmacists for people taking the medication
BaclofenSoma
  • Can cause dizziness and fatigue.
  • Avoid activities requiring mental alertness (like driving) until you know how it affects you.
  • Can cause extreme drowsiness or dizziness if you're taking it with high blood pressure medications.
  • Side effects are more prevalent in the elderly.
  • Don't drink alcohol while using this.
  • Can be taken as needed or 'around-the-clock'. Ask your doctor about what'll work best for you.
  • If taking regularly, you need to work with your doctor to get off the medication slowly (also called tapering) to avoid withdrawal symptoms.
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Not to be used for long-term treatment (2 to 3 weeks maximum)
  • Don't drink alcohol while on this medication.
  • Can cause stomach pain, nausea and vomiting.
Learn more
More about BaclofenSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lioresal (baclofen)?
Worth itNot sureNot worth it
More about SomaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it