Compare baclofen vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lioresal (baclofen)

Prescription only

Soma (carisoprodol)

Prescription only
Relaxes your muscles.

Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.

4.8/ 7 average rating with 33 reviewsforbaclofen
Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

4.7/ 7 average rating with 220 reviewsforSoma
Upsides
  • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
  • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
Downsides
  • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
  • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
  • Lioresal (baclofen) can make you sleepy.
  • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$9.99
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Lowest price near you
$12.75
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Reviews
33 
61%
think this treatment is worth it
55%
think this treatment works well
15%
think this treatment is a hassle

Have you used Lioresal (baclofen)?

Leave a review
220 
61%
think this treatment is worth it
39%
think this treatment works well
9%
think this treatment is a hassle

Have you used Soma (carisoprodol)?

Leave a review
Side effects
1possible side effects
  • Drowsiness
    63%
See more detailed side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
Risks and warnings
  • Withdrawal symptoms

    Stopping Lioresal (baclofen) too quickly

  • Driving impairment

    Taking with alcohol

    ...and 2 more risk factors

  • Seizures

    Higher dose

    ...and 5 more risk factors

See more detailed risks and warnings
  • Sleepiness and dizziness

    Taking other medications that also cause sleepiness

    ...and 3 more risk factors

  • Abuse, dependence and withdrawal

    Prior history of drug abuse

    ...and 1 more risk factors

  • Seizures

    Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol

See more detailed risks and warnings