Compare Bactrim vs. Augmentin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Bactrim (sulfamethoxazole / trimethoprim)

Prescription only
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

5.0/ 7 average rating with 473 reviewsforBactrim
Treats bacterial infections.

Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.

5.3/ 7 average rating with 1034 reviewsforAugmentin
Upsides
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
Downsides
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
Price
Lowest price near you
$4
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Lowest price near you
$300.98
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Reviews
473 
59%
think this treatment is worth it
49%
think this treatment works well
22%
think this treatment is a hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
1034 
68%
think this treatment is worth it
52%
think this treatment works well
13%
think this treatment is a hassle

Have you used Augmentin (amoxicillin / clavulanate)?

Leave a review
Side effects
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
3possible side effects
  • Diarrhea
    15%
  • Vaginal yeast infection
    3%
  • Nausea
    2%
See more detailed side effects
Risks and warnings
  • Lower kidney function

    Elderly

    ...and 1 more risk factors

See more detailed risks and warnings
  • Serious allergic reaction

    History of penicillin allergy

    ...and 1 more risk factors

  • Liver damage

    Existing liver problems

    ...and 1 more risk factors

  • Superinfection

    Taking Augmentin (amoxicillin / clavulanate) for a long time

    ...and 2 more risk factors

  • Rash

    Mononucleosis

See more detailed risks and warnings