Compare Belsomra vs. Doxepin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Belsomra
(suvorexant)

Zonalon
(doxepin)

Helps you sleep. Belsomra (suvorexant) helps you fall asleep, but is only avaliable as a brand name so can be expensive.Helps you stop itching. Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Doxepin
Best available price for 30 (10mg) capsules of doxepin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Belsomra (suvorexant)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Zonalon (doxepin)?
Worth itNot sureNot worth it
Side effects
BelsomraDoxepin
  • Headache 1%
  • Sleepiness 4%
  • Dizziness 1%
  • Diarrhea 1%
  • Dry mouth 1%
  • Cold and flu 1%
  • Abnormal dreams 1%
  • Cough 1%
More Belsomra side effects »

We haven’t found good data for Doxepin side effects.

FDA side effect reports for Doxepin »
How it works
BelsomraDoxepin
Belsomra (suvorexant) is a newer, non-benzodiazepine option that reduces wakefulness and help with sleep by inhibiting the orexin receptors in the brain.Zonalon (Doxepin) is an cream that stops you from itching by blocking the chemical receptors that cause itching.
Type of medication
BelsomraDoxepin
Prescription onlyPrescription only
Available as
BelsomraDoxepin
  • Pill
  • Cream, gel, or ointment
Used for
BelsomraDoxepin
  • Skin Intching Moderate
Risk factors for serious side effects
BelsomraDoxepin
  • Uncontrolled psychiatric conditions
  • Alcohol
  • Other medicines that make you sleepy or dizzy
  • Taking other medicines that make you less alert
Detailed Belsomra (suvorexant) risks & warnings »
    Detailed Zonalon (doxepin) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Price
    BelsomraDoxepin
    No price related info.
    • It isn't available as a generic, so it could be kind of pricey.
    Interactions
    BelsomraDoxepin
    No interactions related info.
    • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
    Alcohol
    BelsomraDoxepin
    • Not safe to take with alcohol or sleeping medications.
    No alcohol related info.
    Sleep
    BelsomraDoxepin
    • If you have COPD or sleep apnea, talk to your doctor first about Belsomra (suvorexant) before starting it. Belsomra (suvorexant) can make it hard to breathe.
    • Only take if you plan to sleep at least 7 hours.
    • May be helpful if other sleep aids don't work.
    • Not recommended if you do not plan to sleep for at least 7 hours.
    • Zonalon (Doxepin) can make you sleepy.
    Upsides and benefits
    BelsomraDoxepin
    • May be helpful if other sleep aids don't work.
    • Works quickly, especially on an empty stomach.
    • Might be a good option for the elderly.
    • In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
    • You can use Zonalon (Doxepin) for up to 8 days at a time.
    Downsides and risks
    BelsomraDoxepin
    • Not usually used for long-term treatment since it can be habit-forming.
    • Belsomra (suvorexant) is likely expensive since it's only available as a brand name, but coupon savings program could be available.
    • Not recommended if you do not plan to sleep for at least 7 hours.
    • Belsomra (suvorexant) may cause sleep paralysis.
    • You need a prescription for Zonalon (Doxepin).
    • It isn't available as a generic, so it could be kind of pricey.
    • Zonalon (Doxepin) can make you sleepy.
    • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
    Tips from our pharmacists for people taking the medication
    BelsomraDoxepin
    • Take Belsomra (suvorexant) 30 minutes before bedtime.
    • Only take if you plan to sleep at least 7 hours.
    • Taking Belsomra (suvorexant) on an empty stomach will quicken the effects.
    • Belsomra (suvorexant) can be addictive and is meant for short-term treatment.
    • Can cause headaches and/or dizziness.
    • Not safe to take with alcohol or sleeping medications.
    • If Belsomra (suvorexant) does not help you sleep after taking it for 10 days, consider talking to your doctor/pharmacist about other potential causes of insominia.
    • Be sure the affected area is clean and dry before applying Zonalon (Doxepin).
    • Wash your hands before and after using it.
    • Apply a thin layer of Zonalon (Doxepin) onto the affected area and rub it in gently.
    • Don’t put a bandage, dressing, or make-up over Zonalon (Doxepin) once it's on your skin.
    • It shouldn't affect you too much, but avoid activities that need you to be fully alert (like driving) until you know how it works.
    Learn more
    More about BelsomraSide effectsAlternativesFDA package insert
    Have you used Belsomra (suvorexant)?
    Worth itNot sureNot worth it
    More about DoxepinSide effectsFDA package insert
    Have you used Zonalon (doxepin)?
    Worth itNot sureNot worth it