Compare Belsomra vs. Doxepin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Belsomra (suvorexant)

Prescription only

Zonalon (Doxepin)

Prescription only
Helps you sleep.

Belsomra (suvorexant) helps you fall asleep, but is only avaliable as a brand name so can be expensive.

Helps you stop itching.

Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.

Upsides
  • May be helpful if other sleep aids don't work.
  • Works quickly, especially on an empty stomach.
  • Might be a good option for the elderly.
  • In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
  • You can use Zonalon (Doxepin) for up to 8 days at a time.
Downsides
  • Not usually used for long-term treatment since it can be habit-forming.
  • Belsomra (suvorexant) is likely expensive since it's only available as a brand name, but coupon savings program could be available.
  • Not recommended if you do not plan to sleep for at least 7 hours.
  • Belsomra (suvorexant) may cause sleep paralysis.
  • You need a prescription for Zonalon (Doxepin).
  • It isn't available as a generic, so it could be kind of pricey.
  • Zonalon (Doxepin) can make you sleepy.
  • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
Used for
  • Skin intching (moderate)
Dosage forms
  • Pill
  • Cream, gel, or ointment
Price
Lowest price near you
$322.31
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Lowest price near you
$9.99
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Reviews
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Side effects
8possible side effects
  • Headache
    7%
  • Sleepiness
    7%
  • Dizziness
    3%
  • Diarrhea
    2%
  • Dry mouth
    2%
  • Cold and flu
    2%
  • Abnormal dreams
    2%
  • Cough
    2%
See more detailed side effects
The Zonalon (Doxepin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Changes in thoughts

    Uncontrolled psychiatric conditions

    ...and 2 more risk factors

  • Hangover effect

    Alcohol

    ...and 2 more risk factors

  • Dependence and withdrawal

    Continuous use for 2 weeks or more

  • Depression

    Risk increases with dose

    ...and 1 more risk factors

  • Difficulty breathing

    Sleep apnea

    ...and 1 more risk factors

See more detailed risks and warnings