Compare Benadryl vs. Dalmane

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benadryl
(diphenhydramine)

Dalmane
(flurazepam)

Treats allergy symptoms and helps you sleep. Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.Helps you fall asleep. Dalmane (flurazepam) helps you fall asleep, but its effect can carry over to the next day and be addictive.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.63Benadryl
Reviews for Benadryl
86%
of people (All ages) say Benadryl is worth it
59%
say it works well
8%
say it's a big hassle
294 reviews
Have you used Benadryl (diphenhydramine)?
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Have you used Dalmane (flurazepam)?
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Side effects
BenadrylDalmane

We haven’t found good data for Benadryl side effects.

FDA side effect reports for Benadryl »

The Dalmane FDA package insert doesn’t have numbers about how common side effects are.

More about Dalmane side effects »
How it works
BenadrylDalmane
Benadryl (Diphenhydramine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions. It also makes you sleepy.Dalmane (flurazepam) is a benzodiazepine. It activates the part of your brain for resting and digesting.
Type of medication
BenadrylDalmane
Prescription or OTCPrescription only
Available as
BenadrylDalmane
  • Pill
  • Oral solution
  • Cream, gel, or ointment
  • Capsule
Used for
BenadrylDalmane
Risk factors for serious side effects
BenadrylDalmane
  • Using other drugs with the same ingredients
  • Age 65 years or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Children age 6 years and younger
Detailed Benadryl (diphenhydramine) risks & warnings »
  • Alcohol
  • Taking narcotics, tranquilizers or antihistamines
  • Women
  • Over age 65
Detailed Dalmane (flurazepam) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
BenadrylDalmane
  • Don't take it with alcohol or other drugs that make you sleepy.
  • Can be dangerous if combined with alcohol or narcotics.
Sleep
BenadrylDalmane
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • People taking Dalmane (flurazepam) for sleep have reported having difficulty concentrating the next day, and have problems driving or operating machinery. Talk to your doctor if this is a problem.
  • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
Upsides and benefits
BenadrylDalmane
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
  • Dalmane (flurazepam) works 15-30 minutes after taking it.
  • Dalmane (flurazepam) is available in generic.
Downsides and risks
BenadrylDalmane
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
  • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
  • Should only be used short-term because it can be addicting.
  • Can cause sleep-walking or other sleep-related activities that you may not remember doing the next day.
Tips from our pharmacists for people taking the medication
BenadrylDalmane
  • Take it as needed every 4 to 6 hours.
  • Benadryl (Diphenhydramine) can make you dehydrated, so avoid this side effect by drinking plenty of fluids.
  • Benadryl (Diphenhydramine) makes you tired, so take it before you go to sleep.
  • Don't take it with alcohol or other drugs that make you sleepy.
  • If you need to use it for more than a few weeks, talk with your doctor. A different medication might work better for you long-term.
  • If you only have itchy or watery eyes, try using just an antihistamine eye drop.
  • Can be dangerous if combined with alcohol or narcotics.
  • Effect lasts long and may carry into the next morning. Take Dalmane (flurazepam) only if you expect to be in bed for full 7-8 hours.
  • Can cause rebound insomnia if you stop taking it, especially if you've been on it for a while.
  • Can cause sleep walking or doing other behaviors while asleep. Talk to your doctor right away if this happens.
Learn more
More about BenadrylSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benadryl (diphenhydramine)?
Worth itNot sureNot worth it
More about DalmaneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dalmane (flurazepam)?
Worth itNot sureNot worth it