Compare Benadryl vs. Nasacort AQ

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benadryl (Diphenhydramine)

Prescription or OTC

Nasacort Aq (Triamcinolone)

Prescription or OTC
Treats allergy symptoms and helps you sleep.

Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.

4.1/ 5 average rating with 294 reviewsforBenadryl
Relieves allergy symptoms.

Nasacort Aq (Triamcinolone) is the only medication in its class available over the counter for treating stuffy and runny nose due to allergies. You have to use it every day for it to work.

3.6/ 5 average rating with 328 reviewsforNasacort AQ
Upsides
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
  • Available over the counter without a prescription.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
Downsides
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
  • Can't be used on as-needed basis. Must be taken every day.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left.
  • Since the medicine in Nasacort Aq (Triamcinolone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
  • Needs to be primed before use and re-primed if not used for more than 2 weeks.
Used for
Dosage forms
  • Pill
  • Oral solution
  • Cream, gel, or ointment
  • Nasal spray
Price
No pricing information available
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Reviews
294 reviews so far
86%
saidit'sworth it
59%
saiditworked well
8%
saidit'sa big hassle

Have you used Benadryl (Diphenhydramine)?

Leave a review
328 reviews so far
67%
saidit'sworth it
39%
saiditworked well
10%
saidit'sa big hassle

Have you used Nasacort Aq (Triamcinolone)?

Leave a review
Side effects
The Benadryl (Diphenhydramine) FDA package insert doesn’t have numbers about how common side effects are.
The Nasacort Aq (Triamcinolone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Overdose
    • Using other drugs with the same ingredients
  • Increased side effects
    • Age 65 years or older
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Hyperactivity
    • Children age 6 years and younger
  • Trouble urinating
    • Enlarged prostate
    • History of bladder problems
  • Vision changes
    • Glaucoma
  • Breastfeeding
    • Nursing mothers
See more detailed risks and warnings
  • Changes in the nasal septum
    • Long-term use
  • Decreased wound healing
    • Surgery or trauma to the nose or sinuses
  • Reduced immune system
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
  • Glaucoma and cataracts
    • Long-term use
  • Adrenal suppression
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Nasacort Aq (Triamcinolone)
  • Decrease in growth in children and teenagers
    • Long-term use
    • Taking more than recommended dose
See more detailed risks and warnings