Compare Benazepril vs. Hyzaar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lotensin
(Benazepril)

Hyzaar
(Losartan / Hydrochlorothiazide)

Lowers blood pressure. Benazepril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Removes extra water from your body. Hyzaar (Losartan / Hydrochlorothiazide) is a good combination blood pressure-lowering medicine to try if your blood pressure is very high.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.4186046511627906Benazepril
Reviews for Lotensin (Benazepril)
63%
of people say Lotensin (Benazepril) is worth it
63%
say it works well
21%
say it's a big hassle

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Side effects
BenazeprilHyzaar
  • Dizziness 2%
  • Headache 2%
More Benazepril side effects »
  • Dizziness 3%
  • Back pain 1%
  • Cough 1%
  • Upper respiratory infection 1%
More Hyzaar side effects »
How it works
BenazeprilHyzaar
Benazepril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Hyzaar (Losartan / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure. Hydrochlorothiazide is a diuretic that removes extra water from your body. Losartan is an angiotensin receptor blocker (ARB) that relaxes your blood vessels to lower you blood pressure and allow more blood and oxygen to get to your heart and other organs.
Type of medication
BenazeprilHyzaar
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Angiotensin receptor blocker
Diuretic
Prescription only
Available as
BenazeprilHyzaar
  • Pill
  • Pill
Used for (click to learn more)
BenazeprilHyzaar
Risk factors for serious side effects
BenazeprilHyzaar
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Lotensin (Benazepril) risks & warnings »
    • Women of childbearing age
    • History of kidney problems
    • African descent
    • Current kidney problems
    • Medicine that affects potassium
    • Use of salt substitute
    • History of sulfa allergies
    • History of gout
    • Current kidney problems
    Detailed Hyzaar (Losartan / Hydrochlorothiazide) risks & warnings »
    Pregnancy category
    BenazeprilHyzaar
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
    • Won't work as well if you have severe kidney problems.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
    • Requires routine blood tests to check kidney function.
    • Hyzaar (Losartan / Hydrochlorothiazide) has a risk of making your kidneys not work as well. It is important to get blood work done to check your kidney function before starting Hyzaar (Losartan / Hydrochlorothiazide) and at least annually after.
    • Hyzaar (Losartan / Hydrochlorothiazide) can affect the potassium level in your body. Too much potassium can cause heart problems and too little potassium can cause muscle problems. Baseline and routine lab tests are needed to measure your potassium and kidney function.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    BenazeprilHyzaar
    • A first-choice blood pressure treatment for many people.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • A first-choice treatment for severe high blood pressure, combining the benefits of two blood pressure-lowering medicines with a single pill.
    • Helpful in getting rid of extra fluids if you have issues with fluid balance (like in congestive heart failure).
    • Most people have few side effects.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    Downsides and risks
    BenazeprilHyzaar
    • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Will make you urinate more often.
    • Requires a yearly blood test to see how the medicine is affecting your electrolytes and kidneys.
    • Needs dose adjustment if you have liver problems.
    • Your skin will be more sensitive to the sun while taking this.
    • Won't work as well if you have severe kidney problems.
    • Shouldn't take if you have a sulfa allergy.
    • Not safe to use if you're pregnant.
    Tips from our pharmacists for people taking the medication
    BenazeprilHyzaar
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Can cause dizziness in the first few days.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • Get your blood pressure, potassium, and kidney function checked 1 week after starting the medicine, then routinely after.
    • Tell your doctor about any dizziness or muscle weakness that doesn't go away.
    • Get immediate medical help if you notice any swelling, especially around your head and neck.
    • Can cause dizziness in the first few days.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    Learn more
    More about BenazeprilSide effectsReviews & ratingsAlternativesFDA package insert
    More about HyzaarSide effectsReviews & ratingsAlternativesFDA package insert