Compare Benemid vs. Colcrys
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Benemid (probenecid) can be used to lower high uric acid levels in people with gout, but it is not a first-choice treatment because it takes a long time to kick in.
Colcrys (colchicine) is a second-choice treatment for gout attacks. Be careful how much you use since it can cause problems with your blood.
- Benemid (probenecid) is available in generic.
- It can raise levels of certain antibiotics in the body and make those antibiotics work better.
- It is recommended as a second-choice medicine to help lower uric acid levels if they're not going down fast enough.
- Colcrys (colchicine) treats and stops sudden gout attacks.
- It can be used to prevent gout when people are first starting on allopurinol.
- Colcrys (colchicine) also treats Familial Mediterranean fever.
- Benemid (probenecid) is not a first-choice treatment for gout because it takes a while to kick in.
- It doesn't work well in people who are using aspirin, or have kidney problems.
- You have to take Benemid (probenecid) 2 times a day. Other stronger drugs for gout are only taken 1 time a day.
- Colcrys (colchicine) doesn't work as well as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids to treat gout attacks.
- Taking Colcrys (colchicine) for too long can cause problems with your blood.
- Doses needs to be changed if you have kidney or liver problems.
- While Colcrys (colchicine) stops the redness and swelling of gout attacks, it doesn't stop the pain.
- If you're taking Colcrys (colchicine) to stop gout flare-ups, you can only use it for 3 to 6 months after your levels have stabilized.
- The capsules (Mitigare) are only approved for prevention, but not treatment of gout.
- Blood disorders
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
- Gout attacks
Taking Benemid (probenecid) for the first few weeks
- Kidney problems
History of kidney problems
- Stomach ulcers
History of esophagus or stomach problems, including ulcers
- Food and medicine interactions
...and 7 more risk factors
- Muscle pain and breakdown
...and 3 more risk factors