Compare Benicar vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benicar
(olmesartan)

Lopressor
(metoprolol tartrate)

Lowers blood pressure. Benicar (olmesartan) is a good blood pressure-lowering medicine that protects your kidneys, but with fewer side effects.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.41Benicar
Reviews for Benicar
65%
of people (All ages) say Benicar is worth it
63%
say it works well
12%
say it's a big hassle
118 reviews
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
+3% better vs. Benicar
47%
+16% better vs. Benicar
15%
+3% better vs. Benicar
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Side effects
BenicarLopressor
  • Dizziness 2%
More Benicar side effects »
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Depression 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Tiredness 10%
  • Dizziness 10%
  • First-degree heart block 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
BenicarLopressor
Benicar (olmesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
BenicarLopressor
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
BenicarLopressor
  • Pill
  • Pill
Used for
BenicarLopressor
Risk factors for serious side effects
BenicarLopressor
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Benicar (olmesartan) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
BenicarLopressor
No food related info.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
Kidneys and liver
BenicarLopressor
  • Benicar (olmesartan) can hurt your kidneys. If you already have some degree of kidney damage, Benicar (olmesartan) could make it worse. It's important to get blood work done to check your kidney function before starting Benicar (olmesartan) and at least once a year while you're still taking it.
  • Requires regular blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
No kidneys and liver related info.
Pain
BenicarLopressor
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
Weight
BenicarLopressor
  • Benicar (olmesartan) has been reported to cause severe diarrhea and weight loss unexplained by other causes. Stay hydrated and notify your doctor if you continue to have more than 3-4 loose stools a day.
No weight related info.
Upsides and benefits
BenicarLopressor
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Available by itself and in combination with different blood pressure medicines in a single pill.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
Downsides and risks
BenicarLopressor
  • Requires regular blood tests to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Recently became a generic, though still relatively expensive.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
BenicarLopressor
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires regular blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
Learn more
More about BenicarSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it