Compare Benicar vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benicar
(olmesartan)

Toprol XL
(metoprolol succinate)

Lowers blood pressure. Benicar (olmesartan) is a good blood pressure-lowering medicine that protects your kidneys, but with fewer side effects.Lowers blood pressure and controls heart rate. Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.41Benicar
Reviews for Benicar
65%
of people (All ages) say Benicar is worth it
63%
say it works well
12%
say it's a big hassle
118 reviews
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it
Reviews for Toprol XL
60%
+5% better vs. Benicar
54%
+9% better vs. Benicar
13%
+1% better vs. Benicar
164 reviews
Have you used Toprol XL (metoprolol succinate)?
Worth itNot sureNot worth it
Side effects
BenicarToprol XL
  • Dizziness 2%
More Benicar side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Skin rash and itching 5%
  • Diarrhea 5%
  • Shortness of breath 3%
  • Slower heartbeat 3%
  • Dizziness/balance problems 1%
More Toprol XL side effects »
How it works
BenicarToprol XL
Benicar (olmesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.Toprol XL (metoprolol succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
BenicarToprol XL
Prescription onlyPrescription only
Available as
BenicarToprol XL
  • Pill
  • Extended release
Used for
BenicarToprol XL
Risk factors for serious side effects
BenicarToprol XL
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Benicar (olmesartan) risks & warnings »
  • Sudden discontinuation of medicine
  • Coronary artery disease
  • Diabetes
  • Hyperthyroidsim
  • Heart failure
Detailed Toprol XL (metoprolol succinate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
BenicarToprol XL
  • Benicar (olmesartan) can hurt your kidneys. If you already have some degree of kidney damage, Benicar (olmesartan) could make it worse. It's important to get blood work done to check your kidney function before starting Benicar (olmesartan) and at least once a year while you're still taking it.
  • Requires regular blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
No kidneys and liver related info.
Weight
BenicarToprol XL
  • Benicar (olmesartan) has been reported to cause severe diarrhea and weight loss unexplained by other causes. Stay hydrated and notify your doctor if you continue to have more than 3-4 loose stools a day.
No weight related info.
Upsides and benefits
BenicarToprol XL
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Available by itself and in combination with different blood pressure medicines in a single pill.
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
Downsides and risks
BenicarToprol XL
  • Requires regular blood tests to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Recently became a generic, though still relatively expensive.
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
BenicarToprol XL
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires regular blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Toprol XL (metoprolol succinate) cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine and let your doctor know if it hasn't improved.
  • It can make you feel tired or give you headaches.
  • Can hide symptoms of low blood sugar, so be careful taking this if you have diabetes.
  • Don't stop taking this medicine suddenly.
  • This is the extended-release version, but it also comes in an immediate-release form, metoprolol tartrate.
Learn more
More about BenicarSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Benicar (olmesartan)?
Worth itNot sureNot worth it
More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Toprol XL (metoprolol succinate)?
Worth itNot sureNot worth it