Compare Benicar vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Benicar (olmesartan)

Prescription only
Lowers blood pressure.

Benicar (olmesartan) is a good blood pressure-lowering medicine that protects your kidneys, but with fewer side effects.

5.4/ 7 average rating with 118 reviewsforBenicar
Lowers blood pressure and controls heart rate.

Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.

5.2/ 7 average rating with 164 reviewsforToprol XL
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Available by itself and in combination with different blood pressure medicines in a single pill.
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
  • Requires regular blood tests to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Recently became a generic, though still relatively expensive.
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Extended release
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Side effects
The Benicar (olmesartan) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Dizziness/balance problems
  • Slower heartbeat
See more detailed side effects
Risks and warnings
  • Birth defects

    Women of childbearing age

  • Worsening kidney problems

    History of kidney problems

  • Swelling in the face and head

    African descent

  • High potassium levels

    Current kidney problems

    ...and 2 more risk factors

  • Low blood pressure

    Taking with alcohol

    ...and 1 more risk factors

See more detailed risks and warnings
  • Heart problems

    Sudden discontinuation of medicine

    ...and 1 more risk factors

  • Masked symptoms of low blood sugar


  • Masked symptoms of overactive thyroid


  • Increased symptoms of heart failure

    Heart failure

  • Increased risks during surgery

    Major surgery requiring anesthesia

  • Trouble breathing (bronchospastic disease)

    History of asthma

    ...and 1 more risk factors

See more detailed risks and warnings